Results 81 to 90 of about 3,883,494 (274)

Optimal provision of distributed reserves under dynamic energy service preferences [PDF]

open access: yes, 2018
We propose and solve a stochastic dynamic programming (DP) problem addressing the optimal provision of regulation service reserves (RSR) by controlling dynamic demand preferences in smart buildings.
Baillieul, John   +2 more
core  

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Predicting Service Reliability - Using Survival Analysis of Customer Fuzzy Satisfaction

open access: yesAsian Journal of Technology Management, 2018
. It had been known that the main objective of adding service was creating value to improve customer satisfaction. Therefore, if customer satisfaction was plotted in time series variable, service reliability function was reflected.
Rahman Dwi Wahyudi   +2 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Friction Coefficient of Wet Clutches as a Function of Service Mileage

open access: yesLubricants
As a core component for efficient variable speed transmission and energy saving, wet clutches are widely used in the transmission systems of energy-saving and new energy vehicles.
Bangzhi Wu
doaj   +1 more source

Security-aware Service Function Chain Deployment Method Based on Deep ReinforcementLearning [PDF]

open access: yesJisuanji kexue
As a key technology to improve the utilization of network resources,service function chain combined with deep reinforcement learning makes it possible to achieve flexible and secure deployment.However,how to effectively deploy service function chains ...
ZHU Ziyi, ZHANG Jianhui, ZENG Junjieand ZHANG Hongyuan
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

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