Results 21 to 30 of about 432,563 (211)

Energy landscapes and functions of supramolecular systems [PDF]

Nature Materials, 2016
By means of two supramolecular systems--peptide amphiphiles engaged in hydrogen-bonded β-sheets, and chromophore amphiphiles driven to assemble by π-orbital overlaps--we show that the minima in the energy landscapes of supramolecular systems are defined by electrostatic repulsion and the ability of the dominant attractive forces to trap molecules in ...
Faifan Tantakitti, Job Boekhoven, Xin Wang, Roman V. Kazantsev, Tao Yu, Jiahe Li, Ellen Zhuang, Roya Zandi, Julia H. Ortony, Christina J. Newcomb, Liam C. Palmer, Gajendra S. Shekhawat, Monica Olvera de la Cruz, George C. Schatz, Samuel I. Stupp   +14 more
openaire   +4 more sources

Jardins, parcs et paysages dans l’œuvre de Hermann Hesse – ou Par-delà nature et culture

Recherches Germaniques, 2020
The distinction between gardens and landscapes often seems obvious according to our Western conception: the first would belong to culture (gardens requiring systematic and visible human intervention), the second to nature (landscapes developing freely ...
Corinne Fournier Kiss
doaj   +1 more source

Functional genomic landscape of acute myeloid leukaemia [PDF]

Nature, 2018
The implementation of targeted therapies for acute myeloid leukaemia (AML) has been challenging because of the complex mutational patterns within and across patients as well as a dearth of pharmacologic agents for most mutational events. Here we report initial findings from the Beat AML programme on a cohort of 672 tumour specimens collected from 562 ...
Tyner, Jeffrey W., Tognon, Cristina E., Bottomly, Dan, Wilmot, Beth, Kurtz, Stephen E., Savage, Samantha L., Long, Nicola, Schultz, Anna Reister, Traer, Elie, Abel, Melissa, Agarwal, Anupriya, Blucher, Aurora, Borate, Uma, Bryant, Jade, Burke, Russell, Carlos, Amy, Carpenter, Richie, Carroll, Joseph, Chang, Bill, Coblentz, Cody, d’Almeida, Amanda, Cook, Rachel, Danilov, Alexey, Dao, Kim-Hien T., Degnin, Michie, Devine, Deirdre, Dibb, James, Edwards, David K., Eide, Chris A., English, Isabel, Glover, Jason, Henson, Rachel, Ho, Hibery, Jemal, Abdusebur, Johnson, Kara, Johnson, Ryan, Junio, Brian, Kaempf, Andy, Leonard, Jessica, Lin, Chenwei, Liu, Selina (Qiuying), Lo, Pierrette, Loriaux, Marc M., Luty, Samuel, Macey, Tara, MacManiman, Jason, Martinez, Jacqueline, Mori, Motomi, Nelson, Dylan, Nichols, Ceilidh, Peters, Jill, Ramsdill, Justin, Rofelty, Angela, Schuff, Robert, Searles, Robert, Segerdell, Erik, Smith, Rebecca L., Spurgeon, Stephen E., Sweeney, Tyler, Thapa, Aashis, Visser, Corinne, Wagner, Jake, Watanabe-Smith, Kevin, Werth, Kristen, Wolf, Joelle, White, Libbey, Yates, Amy, Zhang, Haijiao, Cogle, Christopher R., Collins, Robert H., Connolly, Denise C., Deininger, Michael W., Drusbosky, Leylah, Hourigan, Christopher S., Jordan, Craig T., Kropf, Patricia, Lin, Tara L., Martinez, Micaela E., Medeiros, Bruno C., Pallapati, Rachel R., Pollyea, Daniel A., Swords, Ronan T., Watts, Justin M., Weir, Scott J., Wiest, David L., Winters, Ryan M., McWeeney, Shannon K., Druker, Brian J.   +87 more
openaire   +2 more sources

Statistical modeling of RNA structure profiling experiments enables parsimonious reconstruction of structure landscapes. [PDF]

, 2018
RNA plays key regulatory roles in diverse cellular processes, where its functionality often derives from folding into and converting between structures.
Aviran, Sharon, Li, Hua
core   +2 more sources

The clear cell sarcoma functional genomic landscape [PDF]

Journal of Clinical Investigation, 2021
Clear cell sarcoma (CCS) is a deadly malignancy affecting adolescents and young adults. It is characterized by reciprocal translocations resulting in expression of the chimeric EWSR1-ATF1 or EWSR1-CREB1 fusion proteins, driving sarcomagenesis. Besides these characteristics, CCS has remained genomically uncharacterized.
Emanuele Panza, Benjamin B. Ozenberger, Krystal M. Straessler, Jared J. Barrott, Li Li, Yanliang Wang, Mingchao Xie, Anne Boulet, Simon W.A. Titen, Clinton C. Mason, Alexander J. Lazar, Li Ding, Mario R. Capecchi, Kevin B. Jones   +13 more
openaire   +2 more sources

Impact of danger, legibility and mystery on visitor’s preference in fortified landscapes compared with park landscapes in urban areas

Landscape Online, 2023
Both the parks and historical fortifications constitute important components of urban green spaces in many cities around the world. The approach taken in terms of shaping these spaces often appears similar regardless of provenance.
Łukasz Pardela, Aleksandra Lis, Karolina Zalewska   +2 more
doaj   +1 more source

Avian Diversity in Agricultural Landscapes of SP3 Pangea Area in Gorontalo Province [PDF]

E3S Web of Conferences, 2023
An agroecosystem cannot function without birds, which perform a variety of functions, including pollination, seed dispensing, nutrient deposition, scavenging, and predatory roles for rodents and insect agricultural landscapes support a wide range of ...
Ibrahim Mustamin, Nur Akbar Muh.
doaj   +1 more source

Detecting Repetitions and Periodicities in Proteins by Tiling the Structural Space [PDF]

, 2013
The notion of energy landscapes provides conceptual tools for understanding the complexities of protein folding and function. Energy Landscape Theory indicates that it is much easier to find sequences that satisfy the "Principle of Minimal Frustration ...
Espada, Rocío, Ferreiro, Diego U., Parra, R. Gonzalo, Sippl, Manfred J., Sánchez, Ignacio E.   +4 more
core   +2 more sources

Landscape function analysis as a base of landscape visions [PDF]

Acta Universitatis Sapientiae, Agriculture and Environment, 2015
Abstract An essential condition for the success of rural areas is the harmonious enforcement of ecologic, economic, and other educational, cultural, aesthetic goods/services of landscape, diversity of landscape functions. Landscape function analysis is a useful tool for the complex evaluation of rural regions. Using statistic and spatial
Filepné Kovács Krisztina, Valánszki István, Sallay Ágnes, Jombach Sándor, Mikházi Zsuzsanna, Kollányi László   +5 more
openaire   +2 more sources

Estimating conformational landscapes from Cryo-EM particles by 3D Zernike polynomials

Nature Communications, 2023
Conformational heterogeneity is key to understand how macromolecular function and structure converge. Here, the authors propose an algorithm designed to estimate structural landscapes directly from Cryo-EM particle images.
D. Herreros, R. R. Lederman, J. M. Krieger, A. Jiménez-Moreno, M. Martínez, D. Myška, D. Strelak, J. Filipovic, C. O. S. Sorzano, J. M. Carazo   +9 more
doaj   +1 more source