Results 81 to 90 of about 432,563 (211)

Effects of Epistasis and Pleiotropy on Fitness Landscapes

, 2013
The factors that influence genetic architecture shape the structure of the fitness landscape, and therefore play a large role in the evolutionary dynamics. Here the NK model is used to investigate how epistasis and pleiotropy -- key components of genetic
A Dawid, AI Khan, B Østman, DJ Kvitek, FJ Poelwijk, H Chou, HA Orr, MC Whitlock, MC Whitlock, MM Desai, RL Unckless, S Gavrilets, S Gavrilets, S Kauffman, S Kauffman, V Mustonen   +15 more
core   +1 more source

Efficient Hill Climber for Constrained Pseudo-Boolean Optimization Problems [PDF]

, 2016
Efficient hill climbers have been recently proposed for single- and multi-objective pseudo-Boolean optimization problems. For $k$-bounded pseudo-Boolean functions where each variable appears in at most a constant number of subfunctions, it has been ...
Chicano, Francisco, Tinós, Renato, Whitley, Darrell   +2 more
core   +1 more source

Unsupervised and Supervised Learning over the Energy Landscape for Protein Decoy Selection

Biomolecules, 2019
The energy landscape that organizes microstates of a molecular system and governs the underlying molecular dynamics exposes the relationship between molecular form/structure, changes to form, and biological activity or function in the cell.
Nasrin Akhter, Gopinath Chennupati, Kazi Lutful Kabir, Hristo Djidjev, Amarda Shehu   +4 more
doaj   +1 more source

User Perceptions of Text Mining in Peri-Rural Landscapes and Topic Modeling of Icheon City in the Seoul Metropolitan Region

Land
The purpose of this study is to explore and analyse user perceptions of peri-rural landscapes in the Seoul metropolitan region, using Icheon City as a case study.
Doeun Kim, Junho Park, Yonghoon Son
doaj   +1 more source

Critical properties of complex fitness landscapes [PDF]

, 2010
Evolutionary adaptation is the process that increases the fit of a population to the fitness landscape it inhabits. As a consequence, evolutionary dynamics is shaped, constrained, and channeled, by that fitness landscape.
Adami, Christoph, Hintze, Arend, Østman, Bjørn   +2 more
core  

Graded persistence diagrams and persistence landscapes

, 2021
We introduce a refinement of the persistence diagram, the graded persistence diagram. It is the Mobius inversion of the graded rank function, which is obtained from the rank function using the unary numeral system.
Betthauser, Leo, Bubenik, Peter, Edwards, Parker B.   +2 more
core  

Local Optimal Sets and Bounded Archiving on Multi-objective NK-Landscapes with Correlated Objectives [PDF]

, 2014
The properties of local optimal solutions in multi-objective combinatorial optimization problems are crucial for the effectiveness of local search algorithms, particularly when these algorithms are based on Pareto dominance.
E. Zitzler, H.E. Aguirre, J. Dubois-Lacoste, K. Bringmann, L. Paquete, L. Paquete, L. Paquete, M. Laumanns, M. López-Ibáñez, M.M. Drugan, S. Verel, T. Lust   +11 more
core   +5 more sources

Using landscape metrics to analyse urban spatial patterns in the Metropolitan area of Granada

Anales de Geografía de la Universidad Complutense, 2010
Landscape metrics have been widely used to perform analyses of landscape structure, function and change. Within the last years, these metrics have been recently used to analyse urban landscapes.
Francisco Aguilera Benavente
doaj  

Fitness trade-offs in the evolution of dihydrofolate reductase and drug resistance in Plasmodium falciparum.

PLoS ONE, 2011
BackgroundPatterns of emerging drug resistance reflect the underlying adaptive landscapes for specific drugs. In Plasmodium falciparum, the parasite that causes the most serious form of malaria, antifolate drugs inhibit the function of essential enzymes ...
Marna S Costanzo, Kyle M Brown, Daniel L Hartl   +2 more
doaj   +1 more source

Monotonicity of Fitness Landscapes and Mutation Rate Control [PDF]

, 2016
A common view in evolutionary biology is that mutation rates are minimised. However, studies in combinatorial optimisation and search have shown a clear advantage of using variable mutation rates as a control parameter to optimise the performance of ...
A Kong, AE Eiben, AE Nix, AF Agrawal, AF Agrawal, Alastair Channon, BMR Stadler, CA Aktipis, CA Aktipis, CG Knight, Christopher G. Knight, DR Rokyta, Elizabeth Aston, FC Adams, G Badis, HA Orr, HA Orr, HA Orr, HA Orr, HA Orr, I Bjedov, ID Falco, J Cervantes, J He, JA Visser de, JM Smith, John Aston, L Hadany, M Kimura, MJ McDonald, O Tenaillon, P Schuster, R Ahlswede, R Kassen, R Krašovec, R Poli, RA Fisher, RC MacLean, RJ Woods, Rok Krašovec, Roman V. Belavkin, RS Galhardo, S Banach, S Böttcher, S Collins, S Mazurkiewicz, SJ Freeland, T Bataillon, T Jansen, V Mustonen, WH Zhong, Y Ram   +51 more
core   +4 more sources