Results 161 to 170 of about 2,857,572 (312)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Allergy burden score and lung function impairment in children with asthma: a dose-response cross-sectional study. [PDF]

Eur J Pediatr
Zhao J, Wang Z, Wang Y, Dai Q, Qu S, Ru L.   +5 more
europepmc   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Point-to-Point Macular Structure-Function Relationships in Healthy and Glaucomatous Eyes Using OCT and Microperimetry. [PDF]

J Clin Med
Garcia-Medina JJ, Sobrado-Calvo P, Lopez-Canovas L, Lopez-Bernal MD, Pinazo-Duran MD, Zanon-Moreno V, Del-Rio-Vellosillo M.   +6 more
europepmc   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Local quadratic convergence of polynomial-time interior-point methods for conic optimization problems [PDF]

In this paper, we establish a local quadratic convergence of polynomial-time interior-point methods for general conic optimization problems. The main structural property used in our analysis is the logarithmic homogeneity of self-concordant barrier ...
NESTEROV, Yu., TUNCEL, Levent
core  

A comparison on accuracy of function point, object-oriented function point and class point software size estimation models

วิทยานิพนธ์ (วท.ม.)--จุฬาลงกรณ์มหาวิทยาลัย, 2555การประมาณการซอฟต์แวร์เป็นกิจกรรมหนึ่งที่จำเป็นในการวางแผนโครงการพัฒนาซอฟต์แวร์ เพื่อใช้บริหารจัดการทรัพยากรบุคคล เครื่องมือ ค่าใช้จ่ายและระยะเวลาในการพัฒนาซอฟต์แวร์ วิธีการประมาณการซอฟต์แวร์ที่เลือกมีผลต ...
ชมพูนุช เผ่าประพัธน์
core   +1 more source

Distinguishing near- versus off-critical phase behaviors of intrinsically disordered proteins. [PDF]

Rep Prog Phys
Mitra G, Ghosh S, Ruff KM, Zhang R, Chauhan G, Pappu RV.   +5 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Preschoolers' Early Sentence Comprehension: Comparing Bilingual and Monolingual Children and the Role of Executive Function and Vocabulary Development. [PDF]

Dev Sci
Rodenhurst N, Messenger K.
europepmc   +1 more source