Results 61 to 70 of about 696,919 (285)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Functional differential equations of third order

Electronic Journal of Differential Equations, 2005
In this paper, we consider the third-order neutral functional differential equation with distributed deviating arguments. We give sufficient conditions for the oscillatory behavior of this functional differential equation.
Tuncay Candan, Rajbir S. Dahiya
doaj  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

On the surjectivity conditions of a linear functional differential operator of the second order

Electronic Journal of Qualitative Theory of Differential Equations
Linear second-order functional differential equations without the Volterra condition are studied. Sufficient conditions for the everywhere solvability of the equation (surjectivity of the corresponding functional differential operator) are obtained in ...
Eugene Bravyi
doaj   +1 more source

Weak solutions to problems involving inviscid fluids

, 2015
We consider an abstract functional-differential equation derived from the pressure-less Euler system with variable coefficients that includes several systems of partial differential equations arising in the fluid mechanics.
C Audiard, C Lellis De, CM Dafermos, CM Dafermos, D Bresch, E Chiodaroli, E Chiodaroli, J Lowengrub, L Desvillettes, M Kotschote, M Kotschote, P Antonelli, P Antonelli, S Benzoni-Gavage, S Benzoni-Gavage   +14 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Analytic Solutions of an Iterative Functional Differential Equations Near Regular Points

Journal of Applied Mathematics, 2013
The existence of analytic solutions of an iterative functional differential equation is studied when the given functions are all analytic and when the given functions have regular points.
Lingxia Liu
doaj   +1 more source

The Differential and Functional Equations for a Lie Group Homomorphism are Equivalent [PDF]

, 2009
I prove the "folklore" result that the functional equation for a Lie group homomorphism can be solved by solving the corresponding differential equation.Comment: 3 ...
Svetlichny, George
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Exponential stability in a scalar functional differential equation

Journal of Inequalities and Applications, 2006
We establish a criterion for the global exponential stability of the zero solution of the scalar retarded functional differential equation whose linear part generates a monotone semiflow on the phase space with respect to the exponential ordering ...
Pituk Mihály, Liz Eduardo
doaj