Results 41 to 50 of about 60,152 (261)

A FLOQUET THEORY FOR FUNCTIONAL DIFFERENTIAL EQUATION [PDF]

open access: yesProceedings of the National Academy of Sciences, 1962
Introduction.-Let C denote the space of continuous functions from [-h, 01 into Rm, m-dimensional Euclidean spa.ce, h > 0, with the norm in C given by 111\ = max 1{(u) l, -h s, by x,(u) = x(t + u), -h s u s 0. With this notation (due to Hale4) and the above definitions, we may write the linear functional differential equation with periodic ...
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Dynamics of cell growth: Exponential growth and division after a minimum cell size

open access: yesPartial Differential Equations in Applied Mathematics
In this paper, we consider a mathematical model for cell division using a Pantograph-type nonlocal partial differential equation, accompanied by relevant initial and boundary conditions. This formulation results in a nonlocal singular eigenvalue problem.
M. Mohsin, A.A. Zaidi, B. van Brunt
doaj   +1 more source

A STABILITY THEOREM FOR FUNCTIONAL-DIFFERENTIAL EQUATIONS [PDF]

open access: yesProceedings of the National Academy of Sciences, 1963
A sufficient condition for the asymptotic stability of the trivial solution of a functional differential system is given which generalizes a result of \textit{J. P. Lasalle} [IRE Trans. Circuit Theory 7, 520--527 (1960), \url{http://dx.doi.org/10.1109/TCT.1960.1086720}]. The result is illustrated by means of an example.
openaire   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

A Partial Functional Differential Equation

open access: yesJournal of Mathematical Analysis and Applications, 2001
The author of this interesting paper investigates the partial functional differential equation \[ \partial u(x,t)\partial t =k \partial^2 u(x,t)\partial x^2+ru(x,t-T)[1-u(x,t)], \;\;t\geq 0, \;\;x\in [{}0,\pi ]{} \] under the boundary condition \(u(0,t)=u(\pi ,t)=0\) (\(t>0\)) and \(u(x,s)=\phi (x,s)\), \(-T\leq s\leq 0\), \(0\leq x\leq \pi \).
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

The Coercivity of Functional Differential Equations

open access: yesJournal of Mathematical Sciences, 2014
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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