Results 201 to 210 of about 7,650,207 (262)

Biochar application alters soil properties and microbial gene profiles in a continuous cassava cropping system. [PDF]

PeerJ
Zhu Y, Zhang J, Wei Y, Zhou S, Qin X.
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Valvular Heart Disease as the Main Cause of Acute Heart Failure with Preserved Ejection Fraction: Dynamic Severe Functional Valvular Regurgitation as the Main Mechanism of Decompensation. [PDF]

Card Fail Rev
Bellicini MG.
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Applying the ICF framework in severe traumatic brain injury: functional profiling to guide multidisciplinary rehabilitation-a case report. [PDF]

J Med Case Rep
Chandyoke D, Chandrasekar E.
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Differential Responses of Flowering Functional Groups to Species Loss Altered Community Flowering-Date Synchrony and Reduced Temporal Stability in an Alpine Meadow. [PDF]

Plants (Basel)
Liu P, Xiong S, Chen J, Dai W.
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Unveiling Functional-Metabolic Synergy in the Healthy Brain: Multivariate Integration of Dynamic [¹⁸F]FDG-PET and Resting-State fMRI. [PDF]

Hum Brain Mapp
Tarricone C, Vallini G, Baron G, Facca M, Silvestri E, Volpi T, Vlassenko AG, Goyal MS, Bertoldo A.   +8 more
europepmc   +1 more source