Results 201 to 210 of about 8,080,966 (340)

Functional Analysis [PDF]

Nature, 1956
openaire   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Comprehensive molecular and functional analysis of NUTM1-rearranged leukemia.

Blood
Nishimura K, Isobe T, Shigehiro T, Nomura M, Zang W, Xiao M, Liao W, Koike Y, Nishimura A, Sato-Otsubo A, Yamazaki H, Ito H, Okada S, Matsumoto N, Saika W, Zhang Y, Aoyama Y, Hasegawa C, Yamasaki T, Kubota Y, Ohki K, Kiyokawa N, Nagae G, Yoshida K, Nannya Y, Ueno H, Fukuda S, Tatsuno K, Tsutsumi S, Shiozawa Y, Shiraishi Y, Chiba K, Tanaka H, Eguchi M, Arakawa Y, Koh K, Deguchi T, Tomizawa D, Miyamura T, Ishii E, Mizutani S, Miyano S, Aburatani H, Ogawa S, Takaori-Kondo A, Yokoyama A, Abdel-Wahab O, Ernst P, Takita J, Ikawa T, Takagi M, Inoue D.   +51 more
europepmc   +1 more source

The identification of gibberellin 2-oxidase gene family in cotton and functional analysis. [PDF]

BMC Plant Biol
Wei Y, Feng A, Tuo M, Song S, Zhang Y, Cheng S, Zhang X, Li Y, Sun J.   +8 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Functional Analysis of the Scarlet Gene in the Cricket Gryllus bimaculatus. [PDF]

Insects
Zeng LF, Bai Y, Chen L, Yang XK, Xu JL, He ZQ, Li K.   +6 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Wet Lab Techniques for the Functional Analysis of Circular RNA. [PDF]

Cells
Chakravarthi VP, Christenson LK.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Structural basis and functional analysis of NMDA receptor regulation by calmodulin. [PDF]

J Biol Chem
Bej A, Erickson-Oberg MQ, Nigam A, Yu I, Hell JW, Johnson JW, Ames JB.   +6 more
europepmc   +1 more source