Results 281 to 290 of about 33,941,795 (386)

RGF Gene Family Analysis and Functional Evidence for RGF8-Mediated Salt Stress Tolerance in Brassica Species [PDF]

Shiwei Wang, Feng‐Ping Zhang, Ruyu Jiao, Fan-Xuan Nie, Yilin Zhu, Xian‐Yan Huang, Wenqing Tan, Qian Yang, Xin-Hong Liu, Lili Liu, Duoyan Rong, Zhixiang Liu, Qijun Xie   +12 more
openalex   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Structural and functional analysis of a homotrimeric collagen peptide. [PDF]

Front Bioeng Biotechnol
Zhang X, Li K, Lu N, Takebayashi T, Zhou B, Xie H, Li Y, Long X, Qin X, Zhao H, Dong J.   +10 more
europepmc   +1 more source

S100B Measured in Blood Samples as a Prognostic Biomarker of Functional Capacity and Vital Status in Moderate and Severe Traumatic Brain Injury Patients: Systematic Review and Meta-Analysis

Lillian Caroline Fernandes, Dyenily Alessi Sloboda, T. Martins-Rocha, Lilia de Souza Nogueira, Ramon Antônio Oliveira, Augusto Magno Tranquezi Cordeiro, Wellingson Silva Paiva, Rute Vieira, Leda Leme Talib, Regina Márcia Cardoso de Sousa   +9 more
openalex   +1 more source

Comprehensive sequencing profile and functional analysis of IsomiRs in human pancreatic islets and beta cells [PDF]

Stefano Auddino, Elena Aiello, Giuseppina Emanuela Grieco, Daniela Fignani, Giada Licata, Marco Bruttini, Alessia Mori, Andrea F. Berteramo, E.A. Pedace, Laura Nigi, Caterina Formichi, Claudiane Guay, Giuseppe Quero, Vincenzo Tondolo, Gianfranco Di Giuseppe, Laura Soldovieri, Gea Ciccarelli, Andrea Mari, Andrea Giaccari, Teresa Mezza, Agnese Pò, Romano Regazzi, Francesco Dotta, Guido Sebastiani   +23 more
openalex   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Artificial intelligence-assisted optimization of extraction process, characterization, and functional analysis of globulin from safflower seed meal. [PDF]

Front Nutr
Xiao K, Wang Q, Meng X, Zhao Z, Sai M, Guan L, Lu Q, Gao L, Yang J, Du L.   +9 more
europepmc   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Identification, functional analysis, and clinical applications of defective viral genomes. [PDF]

Front Microbiol
Yan X, Pan Y, Li P, Zhu L, Yu J, Shen C, Zhang B, Zhao W.   +7 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source