Results 121 to 130 of about 2,947,952 (242)

Low-Pressure Microwave Plasma Reduction of Iron and Copper Salt Compounds at Low Temperatures for Oxidation State Alteration and Functional Applications. [PDF]

Materials (Basel), 2023
Weber M, Scheglov A, Dörries W, Meyer JB, Viöl W.   +4 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Emission-tunable manganese(ii) halides: structure-property relationships and functional applications. [PDF]

Chem Sci
Wang C, Li Y, Deng Z.
europepmc   +1 more source

2D Semiconductor Nanomaterials and Heterostructures: Controlled Synthesis and Functional Applications. [PDF]

Nanoscale Res Lett, 2021
Xu H, Akbari MK, Zhuiykov S.
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Exploration of Ruthenium(II/III/VI)-Salen Complexes: From Synthesis to Functional Applications. [PDF]

Molecules
Cristóvão B, Osypiuk D, Bartyzel A.
europepmc   +1 more source

A novel method for the synthesis of core-shell nanoparticles for functional applications based on long-term confinement in a radio frequency plasma. [PDF]

Nanoscale Adv, 2023
Asnaz OH, Drewes J, Elis M, Strunskus T, Greiner F, Polonskyi O, Faupel F, Kienle L, Vahl A, Benedikt J.   +9 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Recent Advances, Challenges, and Functional Applications of Protein Chemical Modification in the Food Industry. [PDF]

Foods
Zhao P, Zhang Z, Ran W, Bai T, Cheng J, Zhang J.   +5 more
europepmc   +1 more source

An In-Depth Study on the Metabolite Profile and Biological Properties of Primula auriculata Extracts: A Fascinating Sparkle on the Way from Nature to Functional Applications. [PDF]

Antioxidants (Basel), 2022
Kurt-Celep I, Zheleva-Dimitrova D, Gevrenova R, Uba AI, Zengin G, Yıldıztugay E, Picot-Allain CMN, Lorenzo JM, Mahomoodally MF, Montesano D.   +9 more
europepmc   +1 more source