Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
On the Simply-Typed Functional Machine Calculus: Categorical Semantics and Strong Normalisation [PDF]
Chris Barrett
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Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
H∞ Functional Calculus and Mikhlin-Type Multiplier Conditions [PDF]
Jośe E. Galé, Pedro J. Miana
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Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah +8 more
wiley +1 more source
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
$H^{\infty}$ functional calculus and square functions on noncommutative $L^p$-spaces [PDF]
Marius Junge +2 more
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On the local everywhere Hölder continuity of the minima of a class of vectorial integral functionals of the calculus of variations [PDF]
Tiziano Granucci
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Autophagosome marker, LC3, is released extracellularly via several distinct pathways
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
1. The calculus of variations and functional analysis with optimal control and applications in mechanics, L. P. Lebedev and M. J. Cloud, WorldScientific, Singapore, 2003, xiii+420pp., Price $94.00, ISBN: 981‐238‐581‐9 2. An introduction to modern variational techniques in mechanics and engineering, B. Z. Vujanovic and T. M. Atanackovic, Birkhäuser, Boston, MA, 2004, x+346pp., Price $74.95, ISBN: 0‐8176‐3399‐5 [PDF]
D. Subbaram Naidu
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