Results 161 to 170 of about 26,719 (309)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

How to prove similarity a precongruence in non-deterministic call-by-need lambda calculi

, 2006
Extending the method of Howe, we establish a large class of untyped higher-order calculi, in particular such with call-by-need evaluation, where similarity, also called applicative simulation, can be used as a proof tool for showing contextual preorder ...
Mann, Matthias, Schmidt-Schauß, Manfred
core  

ON THE OPERATIONAL CALCULUS WITH DIFFERENTIABLE FUNCTIONS [PDF]

Proceedings of the National Academy of Sciences, 1958
openaire   +2 more sources

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Functional Computation in a Uniformly Concurrent Calculus

, 1994
Liegt nicht vor.The thesis is written in German, but will be translated soon. English title: Functional Computation in a Uniformly Concurrent Calculus with Logic Variables. We present the delta-calculus, a model of uniformly concurrent computation.
Niehren, Joachim
core  

Realm Calculus VII: Calculus of Variations and Functional Calculus

Paper VII develops the variational and functional calculus chapter of the Realm Calculus framework. It establishes realm aware action principles, realm Euler Lagrange equations with anomaly residue, realm Hamiltonian formulation with asymmetric Legendre transform, realm Noether theorem with a two trace conservation law, realm Hamilton Jacobi equation ...
openaire   +3 more sources

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Insights into demographic and cultural influences on the oral microbiome from historical Japanese dental calculus. [PDF]

Sci Rep
Kuriyama Y, Mizuno F, Yamada T, Kumagai M, Tanaka M, Naka I, Hirata K, Mizushima S, Yonemoto S, Funahashi K, Seguchi N, Sakaue K, Kanazawa E, Matsushita M, Matsushita T, Saso A, Nara T, Sawaura R, Katagiri C, Maekawa T, Kurosaki K, Saitoh H, Namiki S, Ueda S, Ohashi J.   +24 more
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source