Results 71 to 80 of about 3,034,015 (300)

On the capacity functional of excursion sets of Gaussian random fields on $\R^2$ [PDF]

open access: yes, 2014
When a random field $(X_t, \ t\in {\mathbb R}^2)$ is thresholded on a given level $u$, the excursion set is given by its indicator $~1_{[u, \infty)}(X_t)$.
Kratz, Marie, Nagel, Werner
core   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Assessment of the Functional Status of Patients after Ischemic Stroke Treated with Thrombolytic Therapy

open access: yesPielęgniarstwo Neurologiczne i Neurochirurgiczne
Introduction. One of the most effective methods for treating acute ischemic stroke is thrombolytic therapy, which involves intravenous administration of recombinant tissue plasminogen activator (rtPA) within a narrow therapeutic window of up to 4.5 hours
Danuta Sternal   +4 more
doaj   +1 more source

Locomotion in Response to Shifting Climate Zones: Not So Fast [PDF]

open access: yes, 2010
Although a species’ locomotor capacity is suggestive of its ability to escape global climate change, such a suggestion is not necessarily straightforward. Species vary substantially in locomotor capacity, both ontogenetically and within/among populations,
Feder, Martin E.   +3 more
core   +1 more source

Three-year follow-up study exploring metacognition and function in individuals with first episode psychosis [PDF]

open access: yes, 2019
Introduction: Research has demonstrated that functional outcome in psychosis is predicted by factors such as neurocognition, functional capacity, symptoms and, more recently, metacognition.
Allott   +112 more
core   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Pulmonary rehabilitation program of 36 sessions improves functional capacity and reduce body mass level in patients with chronic obstructive pulmonary disease

open access: yesRevista Brasileira de Prescrição e Fisiologia do Exercício, 2022
Aim: To evaluate the functional capacity through the 6-minutes walk test and the body mass level in patients with Chronic Pulmonary Obstructive Disease, Pulmonary Rehabilitation Program participants, in pre moments, 18 sessions and in the end of 36 ...
Paulo Sergio Correia Martins   +6 more
doaj  

Titanium-capped carbon chains as promising new hydrogen storage media

open access: yes, 2010
The capacity of Ti-capped sp carbon atomic chains for use as hydrogen storage media is studied using first-principles density functional theory. The Ti atom is strongly attached at one end of the carbon chains via d-p hybridization, forming stable TiCn ...
Bogana   +28 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

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