Results 191 to 200 of about 5,609,232 (306)

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Functional classification of platelet gene variants using CRISPR HDR in CD34⁺ cell-derived megakaryocytes. [PDF]

Am J Hum Genet
Kosaka Y, Lopez B, Kishimoto N, Jacob S, Montenont E, Huallanca R, Coughenour G, Di Paola J, Ross J, Lee K, Rondina MT, Bray PF, Rowley JW.   +12 more
europepmc   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Gross motor functional classification for arthrogryposis multiplex congenita: protocol for co-development involving public with lived and professional experience. [PDF]

Res Involv Engagem
Araujo CRS, Hyer L, Sienko SE, Buckon C, Costa C, Natera-de Benito D, Donohoe M, Donlevie K, Emblin M, Fafara A, Sullivan JC, Dahan-Oliel N, AMC Registry Team members.   +12 more
europepmc   +1 more source

Transcriptome-guided annotation and functional classification of long non-coding RNAs in Arabidopsis thaliana. [PDF]

Sci Rep, 2022
Corona-Gomez JA, Coss-Navarrete EL, Garcia-Lopez IJ, Klapproth C, Pérez-Patiño JA, Fernandez-Valverde SL.   +5 more
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Functional classification of GNAI1 disorder variants in Caenorhabditis elegans uncovers conserved and cell-specific mechanisms of dysfunction. [PDF]

Genetics
Salama R, Peet E, Morrione TL, Durant S, Seager M, Rennie M, Scarlata S, Nechipurenko I.   +7 more
europepmc   +1 more source

Functional Classification and Characterization of the Fungal Glycoside Hydrolase 28 Protein Family. [PDF]

J Fungi (Basel), 2022
Villarreal F, Stocchi N, Ten Have A.
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Anatomical versus functional classification of ankyloglossia and their association with temporomandibular joint disorders in adults: a cross sectional study. [PDF]

J Oral Facial Pain Headache
Beckmann A, Peroz I, Peroz S.
europepmc   +1 more source