Results 101 to 110 of about 838,497 (309)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Applied Functional Data Classification

, 2018
Picomole is a New Brunswick based company developing a lung cancer diagnosis system based on a person’s breath sample. Picomole conducted two different studies in an effort to ascertain whether their breath analysis system utilizing cavity ringdown ...
Babyn, Jonathan
core  

Reproducibility and validity of the Functional Communication Classification System for young children with cerebral palsy

, 2021
Aim: To examine interrater agreement and validity of the Functional Communication Classification System (FCCS) for young children with cerebral palsy (CP) aged 2 or 3 years.
Tanya A Rose, Rose, Tanya A, Caynes, Katy, Robert S Ware, Johnston, Leanne M, Katy Caynes, Burmester, Debbie, Ware, Robert S, Debbie Burmester, Leanne M Johnston   +9 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

ATRIAL FIBRILLATION: FUNCTIONAL CLASSIFICATION

Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2020
In article, we studied the heart biomechanics and main arteries kinetics in different types of atrial fibrillation. We described the increase of main hemodynamic parameters in atrial fibrillation.
A. V. Germanov, O. A. Germanova, V. A. Germanov, I. O. Prokhorenko   +3 more
doaj  

WebCARMA: a web application for the functional and taxonomic classification of unassembled metagenomic reads

, 2009
Gerlach W, Jünemann S, Tille F, Goesmann A, Stoye J. WebCARMA: a web application for the functional and taxonomic classification of unassembled metagenomic reads. BMC Bioinformatics.
Jünemann, Sebastian, Stoye Jens, Sebastian Jünemann, Goesmann, Alexander ; https://orcid.org/, Goesmann Alexander, Tille Felix, Gerlach Wolfgang, Jens Stoye, Wolfgang Gerlach, Gerlach, Wolfgang, Stoye, Jens ; https://orcid.org/, Jünemann Sebastian, Tille, Felix, Felix Tille, Alexander Goesmann   +14 more
core   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Experimental condition selection in whole-genome functional classification

, 2004
Microarray technologies enable the quantitative simultaneously monitoring of expression levels for thousands of genes under various experimental conditions.
Wong, K.W., Zhu, Z., Seow, K.T., Ong, Y.S.   +3 more
core   +1 more source

An experimental comparison of classification algorithms for hierarchical prediction of protein function [PDF]

, 2007
Some data can be naturally organised as a hierarchy of classes. The classification of data in such a hierarchy poses some unique challenges to data miners. One particular case of this is the classification of GPCR proteins by their function.
Matthew N. Davies, Timmis, Jon, Miguel Mendao, Flower, Darren R., Secker, Andrew D., Jon Timmis, Mendao, Miguel, Alex A. Freitas, Davies, Matthew N., Andrew Secker, Freitas, Alex A., Darren R. Flower   +11 more
core  

A Bayesian Nonparametric Approach for Functional Data Classification with Application to Hepatic Tissue Characterization [PDF]

, 2015
Computed tomography perfusion (CTp) is an emerging functional imaging technology that provides a quantitative assessment of the passage of fluid through blood vessels.
Marina Vannucci, Fronczyk, Kassandra M., Michele Guindani, Hobbs, Brian P., Chaan S. Ng, Ng, Chaan S., Hobbs, Brian P, Brian P. Hobbs, Ng, Chaan S, Vannucci, Marina, Guindani, Michele, Fronczyk, Kassandra M, Kassandra M. Fronczyk   +12 more
core   +1 more source