Results 191 to 200 of about 5,602,034 (307)

Gross motor functional classification for arthrogryposis multiplex congenita: protocol for co-development involving public with lived and professional experience. [PDF]

Res Involv Engagem
Araujo CRS, Hyer L, Sienko SE, Buckon C, Costa C, Natera-de Benito D, Donohoe M, Donlevie K, Emblin M, Fafara A, Sullivan JC, Dahan-Oliel N, AMC Registry Team members.   +12 more
europepmc   +1 more source

Transcriptome-guided annotation and functional classification of long non-coding RNAs in Arabidopsis thaliana. [PDF]

Sci Rep, 2022
Corona-Gomez JA, Coss-Navarrete EL, Garcia-Lopez IJ, Klapproth C, Pérez-Patiño JA, Fernandez-Valverde SL.   +5 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Functional classification of GNAI1 disorder variants in Caenorhabditis elegans uncovers conserved and cell-specific mechanisms of dysfunction. [PDF]

Genetics
Salama R, Peet E, Morrione TL, Durant S, Seager M, Rennie M, Scarlata S, Nechipurenko I.   +7 more
europepmc   +1 more source

Functional Classification and Characterization of the Fungal Glycoside Hydrolase 28 Protein Family. [PDF]

J Fungi (Basel), 2022
Villarreal F, Stocchi N, Ten Have A.
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Anatomical versus functional classification of ankyloglossia and their association with temporomandibular joint disorders in adults: a cross sectional study. [PDF]

J Oral Facial Pain Headache
Beckmann A, Peroz I, Peroz S.
europepmc   +1 more source

Functional classification of left ventricular remodelling: prognostic relevance in myocardial infarction. [PDF]

ESC Heart Fail, 2022
Chimed S, van der Bijl P, Lustosa R, Fortuni F, Montero-Cabezas JM, Ajmone Marsan N, Gersh BJ, Delgado V, Bax JJ.   +8 more
europepmc   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

H₂O₂ and NO₂^- in Exhaled Breath Condensate Increase After a Wheelchair Rugby Match in Paralympic Athletes: A Possible Effect of Functional Classification. [PDF]

Antioxidants (Basel)
Rosales-Antequera C, Caballero S, Viscor G, Carbonell T, Araneda OF.   +4 more
europepmc   +1 more source