Results 61 to 70 of about 5,609,232 (306)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

How do Government Expenditures by Function Affect Economic Growth? Evidence from Indonesia

Ekuilibrium: Jurnal Ilmiah Bidan Ilmu Ekonomi
This study addresses a key gap in the empirical literature on fiscal policy and economic growth: while numerous studies assess the impact of total government spending, few examine the differential effects of expenditures by function under the COFOG ...
Rido Parulian Panjaitan, Renny Sukmono, Muhammad Syahrul Fuady, Nurfiryal Salsabila, Farhan Hadiantoro   +4 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Effects of Salinity Accumulation on Physical, Chemical, and Microbial Properties of Soil under Rural Domestic Sewage Irrigation

Agronomy
Under irrigation with saline wastewater, SO42−, Cl−, and Ca2+ aggregated in the topsoil, and Mg2+ was significantly higher in the deeper soil than in the topsoil and 40 cm soil layers.
Weihan Wang, Dandan Zhang, Hao Kong, Gengtao Zhang, Feng Shen, Zhiping Huang   +5 more
doaj   +1 more source

Re-purposing software for functional characterization of the microbiome

Microbiome, 2021
Background Widespread bioinformatic resource development generates a constantly evolving and abundant landscape of workflows and software. For analysis of the microbiome, workflows typically begin with taxonomic classification of the microorganisms that ...
Laura-Jayne Gardiner, Niina Haiminen, Filippo Utro, Laxmi Parida, Ed Seabolt, Ritesh Krishna, James H. Kaufman   +6 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Classification of autism spectrum disorder using supervised learning of brain connectivity measures extracted from synchrostates

, 2014
Objective. The paper investigates the presence of autism using the functional brain connectivity measures derived from electro-encephalogram (EEG) of children during face perception tasks. Approach.
Oprescu, Ioana-Anastasia, Das, Saptarshi, Maharatna, Koushik, Sicca, Federico, Jamal, Wasifa, Apicella, Fabio   +5 more
core   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Is personality reflected in the gestures of second language speakers?

Frontiers in Psychology
Previous studies on gestures and personality suggest an ambiguous picture of the effects of the various personality dimensions on the different types of speech-gestures and adaptors.
Renia Lopez-Ozieblo
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source