Results 131 to 140 of about 5,602,034 (307)

An experimental comparison of classification algorithms for hierarchical prediction of protein function [PDF]

open access: yes, 2007
Some data can be naturally organised as a hierarchy of classes. The classification of data in such a hierarchy poses some unique challenges to data miners. One particular case of this is the classification of GPCR proteins by their function.
Matthew N. Davies   +11 more
core  

KOG functional classification.

open access: yes, 2015
KOG functional classification.
Ran Tang (175386)   +3 more
core   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Modelling intra-daily volatility by functional data analysis: an empirical application to the spanish stock market [PDF]

open access: yes, 2009
We propose recent functional data analysis techniques to study the intra-daily volatility. In particular, the volatility extraction is based on functional principal components and the volatility prediction on functional AR(1) models.
Ruiz Ortega, Esther   +8 more
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Functional model-based curve clustering for discovering temporal patterns in chronological corpora

open access: yes, 2012
In many applications of textual analysis corpora are characterized by a temporal structure, i.e. they include texts which have a chronological order (e.g.: political discourses, institutional documents, articles published in newspapers, messages posted ...
Trevisani, Matilde   +2 more
core  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Improving functional classification performance through diversity: the functional voting approach

open access: yes
In recent decades, Functional Data Analysis (FDA) has become widely popular as a framework for ana- lyzing data that are inherently functions in the domain of time.
Maturo Fabrizio   +2 more
core  

Food hydrocolloids: Classification, functional properties and applications

open access: yesПищевые системы
Food hydrocolloids are among the most popular ingredients in the food industry. They act as thickeners, gelling agents, emulsifiers, stabilizers, fat replacers, clarifying agents, flocculants, and foaming agents.
N. V. Nepovinnykh, O. N. Petrova
doaj   +1 more source

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