Results 91 to 100 of about 5,057,856 (264)

DEPTH-BASED CLASSIFICATION FOR FUNCTIONAL DATA [PDF]

open access: yes
Classification is an important task when data are curves. Recently, the notion of statistical depth has been extended to deal with functional observations.
Juan Romo, Sara Lopez-Pintado
core  

A functional classification of metropolitan communities [PDF]

open access: yesDemography, 1973
Abstract Five major approaches to the functional classification of communities have been offered. Although most of them allow the recognition of a community as specialized in more than one function, their application necessitates consideration of the several individual functions one at a time.
openaire   +2 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Functional classification systems and their association with botulinum toxin type a use in pediatric cerebral palsy

open access: yesScientific Reports
Botulinum toxin type A (BoNT-A) is a key intervention for the management of spasticity in children with cerebral palsy (CP); however, the functional factors associated with its use remain incompletely defined.
Duygu Kurtuluş   +2 more
doaj   +1 more source

Functional classification and gene enrichment analysis.

open access: yes, 2016
Functional classification and gene enrichment analysis.
Debora Olioso (3342434)   +7 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Relationship between functional capacity and socioeconomic status in a cohort of Turkish heart failure patients

open access: yesTürk Kardiyoloji Derneği Arşivi, 2016
Objective: New York Heart Association (NYHA) classification predicts prognosis for heart failure (HF) patients. Socioeconomic status (SES) has the potential to affect treatment strategy and disease course.
Hakkı Kaya   +10 more
doaj   +1 more source

Daatset S1 - SEED Subsystems Functional Classification

open access: yes, 2013
SEED Subsystems functional classification of metagenomic contigs.
Michael Abrams (428834)   +2 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

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