Results 101 to 110 of about 5,602,034 (307)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

DEPTH-BASED CLASSIFICATION FOR FUNCTIONAL DATA [PDF]

open access: yes
Classification is an important task when data are curves. Recently, the notion of statistical depth has been extended to deal with functional observations.
Juan Romo, Sara Lopez-Pintado
core  

Functional Random Forest for Biomedical Signals Classification and Interpretative Tools

open access: yes, 2022
This study deals with tree-based techniques and functional data analysis (FDA) [1] for supervised classification of curves representing high-dimensional biomedical data recorded over time.
Fabrizio, Maturo, Rosanna, Verde
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Applied Functional Data Classification

open access: yes, 2018
Picomole is a New Brunswick based company developing a lung cancer diagnosis system based on a person’s breath sample. Picomole conducted two different studies in an effort to ascertain whether their breath analysis system utilizing cavity ringdown ...
Babyn, Jonathan
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Wavelet-RKHS-based functional statistical classification

open access: yes, 2012
A functional classification methodology, based on the Reproducing Kernel Hilbert Space (RKHS) theory, is proposed for discrimination of gene expression profiles.
Rincón Hidalgo, Margarita María; Ruiz Medina, María Dolores
core  

Network-level functional classification results.

open access: yes, 2021
Network-level functional classification results.
Ulrike Kuhl (11507258)   +2 more
core   +1 more source

ATRIAL FIBRILLATION: FUNCTIONAL CLASSIFICATION

open access: yesВестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2020
In article, we studied the heart biomechanics and main arteries kinetics in different types of atrial fibrillation. We described the increase of main hemodynamic parameters in atrial fibrillation.
A. V. Germanov   +3 more
doaj  

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