Results 61 to 70 of about 5,602,034 (307)

An Evolutionary Classification of Genomic Function [PDF]

Genome Biology and Evolution, 2015
The pronouncements of the ENCODE Project Consortium regarding "junk DNA" exposed the need for an evolutionary classification of genomic elements according to their selected-effect function. In the classification scheme presented here, we divide the genome into "functional DNA," that is, DNA sequences that have a selected-effect function, and "rubbish ...
Graur, Dan, Zheng, Yichen, Azevedo, Ricardo B.R.   +2 more
openaire   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Behavioral strategies in critical moments in judo for athletes with visual impairments: a performance analysis according to sport class, sex, and weight category

Revista de Artes Marciales Asiáticas
This study aimed to investigate the behavioral strategies employed during critical moments of judo matches by athletes with visual impairments, comparing performance across sport classes (J1 and J2), sexes, and weight categories at the Paris 2024 ...
Rômulo Sena, Rafael Lima Kons, Daniele Detanico   +2 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Sports Analysis of Wheelchair Basketball Game Statistics

Applied Sciences
Game statistics are used for the analysis of the performance of athletes. This allows the strengths and weaknesses of the players to be understood, and to design and implement training sessions for performance enhancement.
Víctor Hernández-Beltrán, Sergio J. Ibáñez, Mário C. Espada, José M. Gamonales   +3 more
doaj   +1 more source

Functional Classification of Children with Cerebral Palsy in Krapina-Zagorje County

Acta Clinica Croatica, 2021
The aim was to study functional abilities and to create functional classification of children with cerebral palsy (CP) in Krapina-Zagorje County, based on the classification of gross and fine motor skills and associated impairments.
Sunčica Martinec, Gordana Cesarec, Ana Marija Tomečak Krilić, Tomislav Radošević, Žarko Bakran, Vlatka Mejaški Bošnjak   +5 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Classification of autism spectrum disorder using supervised learning of brain connectivity measures extracted from synchrostates

, 2014
Objective. The paper investigates the presence of autism using the functional brain connectivity measures derived from electro-encephalogram (EEG) of children during face perception tasks. Approach.
Oprescu, Ioana-Anastasia, Das, Saptarshi, Maharatna, Koushik, Sicca, Federico, Jamal, Wasifa, Apicella, Fabio   +5 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source