Results 71 to 80 of about 5,609,232 (306)

A hierarchical classification ant colony algorithm for predicting gene ontology terms [PDF]

open access: yes, 2009
This paper proposes a novel Ant Colony Optimisation algorithm for the hierarchical problem of predicting protein functions using the Gene Ontology (GO).
Otero, Fernando E.B.   +5 more
core   +1 more source

Nonparametric regression and classification with functional, categorical, and mixed covariates

open access: yes, 2022
This article is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/).We consider nonparametric prediction with multiple covariates, in particular categorical or functional predictors, or a
Gertheiss, Jan, Selk, Leonie
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Experimental condition selection in whole-genome functional classification [PDF]

open access: yes, 2004
Microarray technologies enable the quantitative simultaneously monitoring of expression levels for thousands of genes under various experimental conditions.
Wong, K.W.   +3 more
core  

What Does Aspect−Oriented Programming Mean for Functional Programmers? [PDF]

open access: yes, 2009
Aspect-Oriented Programming (AOP) aims at modularising crosscutting concerns that show up in software. The success of AOP has been almost viral and nearly all areas in Software Engineering and Programming Languages have become "infected" by the AOP bug ...
Oliveira, BCDS   +7 more
core   +1 more source

Functional classification of secondary lymphedema

open access: yesAnnals of Medicine and Surgery, 2019
The epidemiological classifications of primary lymphedema based on age at emergence and the severity of the edema are fundamental to the transmission of information about this condition. In the secondary type, the lymphatic system is intact at birth but is injured during the course of life, causing a deficiency that leads to lymphedema.
Jose Maria Pereira de Godoy   +1 more
openaire   +2 more sources

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Functional classification of COG.

open access: yes, 2022
Functional classification of COG.
Zhijun Zhao (784822)   +7 more
core   +1 more source

Behavioral strategies in critical moments in judo for athletes with visual impairments: a performance analysis according to sport class, sex, and weight category

open access: yesRevista de Artes Marciales Asiáticas
This study aimed to investigate the behavioral strategies employed during critical moments of judo matches by athletes with visual impairments, comparing performance across sport classes (J1 and J2), sexes, and weight categories at the Paris 2024 ...
Rômulo Sena   +2 more
doaj   +1 more source

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