Results 91 to 100 of about 5,602,034 (307)

Regional functional classification results.

, 2021
Regional functional classification results.
Ulrike Kuhl (11507258), Sarah Sobotta (11507261), Michael A. Skeide (9553046)   +2 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Functional profiling of LDLR variants: Important evidence for variant classification: Functional profiling of LDLR variants

, 2022
Background: Familial Hypercholesterolemia (FH) is a semidominant disorder of the lipid metabolism associated with premature atherosclerosis and coronary heart disease.
Zimon, Magdalena, Pepperkok, Rainer, Bourbon, Mafalda, Graça, Rafael, Alves, Ana Catarina   +4 more
core   +1 more source

Relationship between functional capacity and socioeconomic status in a cohort of Turkish heart failure patients

Türk Kardiyoloji Derneği Arşivi, 2016
Objective: New York Heart Association (NYHA) classification predicts prognosis for heart failure (HF) patients. Socioeconomic status (SES) has the potential to affect treatment strategy and disease course.
Hakkı Kaya, Meltem Refiker Ege, Ali Zorlu, Osman Beton, Hasan Güngör, Ahmet Temizhan, Yeşim Güray, Yüksel Çavuşoğlu, Mehdi Zoghi, Mehmet Birhan Yılmaz, On Behalf Of TREAT-HF Investigators   +10 more
doaj   +1 more source

A functional classification of metropolitan communities [PDF]

Demography, 1973
Abstract Five major approaches to the functional classification of communities have been offered. Although most of them allow the recognition of a community as specialized in more than one function, their application necessitates consideration of the several individual functions one at a time.
openaire   +2 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Functional classification of unigenes.

, 2017
(A) COG (Clusters of Orthologous Groups) functional classification of unigenes; (B) KOG (Eukaryotic Ortholog Groups) functional classification of unigenes.
Chuankun Zhu (500656), Zhengjun Pan (3746665), Guoliang Chang (1575832), Hui Wang (30400), Nan Wu (200090), Huaiyu Ding (3746668)   +5 more
core   +1 more source

WebCARMA: a web application for the functional and taxonomic classification of unassembled metagenomic reads [PDF]

, 2009
Gerlach W, Jünemann S, Tille F, Goesmann A, Stoye J. WebCARMA: a web application for the functional and taxonomic classification of unassembled metagenomic reads. BMC Bioinformatics.
Jünemann, Sebastian, Stoye Jens, Sebastian Jünemann, Goesmann, Alexander ; https://orcid.org/, Goesmann Alexander, Tille Felix, Gerlach Wolfgang, Jens Stoye, Wolfgang Gerlach, Gerlach, Wolfgang, Stoye, Jens ; https://orcid.org/, Jünemann Sebastian, Tille, Felix, Felix Tille, Alexander Goesmann   +14 more
core   +1 more source

Long-Term Outcome after Pneumonectomy at Siriraj Hospital

Siriraj Medical Journal, 2020
Objective: The purpose of this study is to identify predictors of long term survival following pneumonectomy and compare New York Heart Association (NYHA) functional classification and ECOG performance status before and after surgery at Siriraj Hospital.
Wanchai Wongkornrat, Somchai Sriyoscharti, Teeravit Phanchaipetch, Thaworn Subtaweesin, Punnarerk Thongchareon, Pranya Sakiyalak, Worawong Slisatkorn, Akarin Nimmannit, Pansak Laksanabunsong   +8 more
doaj