Results 31 to 40 of about 253,481 (266)

Juvenile myoclonic epilepsy has hyper dynamic functional connectivity in the dorsolateral frontal cortex

NeuroImage: Clinical, 2019
Purpose: Characterize the static and dynamic functional connectivity for subjects with juvenile myoclonic epilepsy (JME) using a quantitative data-driven analysis approach.
Yanlu Wang, Ivanka Savic Berglund, Martin Uppman, Tie-Qiang Li   +3 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

fMRI-Based Static and Dynamic Functional Connectivity Analysis for Post-Stroke Motor Dysfunction Patient: A Review

IEEE Access
Functional magnetic resonance imaging (fMRI) has emerged as a prevalent tool for investigating motor deficits and rehabilitation in the context of stroke.
Kaichao Wu, Beth Jelfs, Katrina Neville, Aiqun Cai, Qiang Fang   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Aberrant Resting-State Cerebellar-Cerebral Functional Connectivity in Methamphetamine-Dependent Individuals After Six Months Abstinence

Frontiers in Psychiatry, 2020
BackgroundStructural and functional alterations in the cerebellum have been consistently reported in addiction literatures. However, evidence implicating the resting-state cerebellar-cerebral functional connectivity in methamphetamine (MA) use disorder ...
Xiaotong Li, Hang Su, Na Zhong, Tianzhen Chen, Jiang Du, Ke Xiao, Ding Xu, Weidong Song, Haifeng Jiang, Min Zhao, Min Zhao, Min Zhao, Min Zhao   +12 more
doaj   +1 more source

Abnormal intra- and inter-network functional connectivity of brain networks in early-onset Parkinson’s disease and late-onset Parkinson’s disease

Frontiers in Aging Neuroscience, 2023
ObjectiveThe purpose of this study is to look into the altered functional connectivity of brain networks in Early-Onset Parkinson’s Disease (EOPD) and Late-Onset Parkinson’s Disease (LOPD), as well as their relationship to clinical symptoms.MethodsA ...
Fan Zhou, ChangLian Tan, Chendie Song, Min Wang, Jiaying Yuan, Yujing Liu, Sainan Cai, QinRu Liu, Qin Shen, Yuqing Tang, Xu Li, Haiyan Liao   +11 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Are current etiological theories of Alzheimer’s disease falsifiable? An epistemological assessment

Frontiers in Aging Neuroscience
Alzheimer’s disease (AD) research is plagued by a proliferation of competing etiological theories, often coexisting without undergoing systematic critical comparison. This article examines the epistemological limitations of the traditional falsifiability
Tommaso Costa, Tommaso Costa, Tommaso Costa, Donato Liloia, Donato Liloia   +4 more
doaj   +1 more source

Altered Domain Functional Network Connectivity Strength and Randomness in Schizophrenia

Frontiers in Psychiatry, 2019
Functional connectivity is one of the most widely used tools for investigating brain changes due to schizophrenia. Previous studies have identified abnormal functional connectivity in schizophrenia patients at the resting state brain network level.
Victor M. Vergara, Victor M. Vergara, Victor M. Vergara, Eswar Damaraju, Jessica A. Turner, Jessica A. Turner, Godfrey Pearlson, Godfrey Pearlson, Aysenil Belger, Daniel H. Mathalon, Daniel H. Mathalon, Steven G. Potkin, Adrian Preda, Jatin G. Vaidya, Theo G. M. van Erp, Theo G. M. van Erp, Sarah McEwen, Vince D. Calhoun, Vince D. Calhoun, Vince D. Calhoun, Vince D. Calhoun, Vince D. Calhoun   +21 more
doaj   +1 more source

Compositions of continuous functions and connected functions [PDF]

Proceedings of the American Mathematical Society, 1992
Suppose f : X → Y f:X \to Y is continuous and onto and g : Y → Z g:Y \to Z is such that g ∘ f : X → Z g \circ f:X \to Z has a property we are interested in. For which properties of
Kellum, Kenneth R., Rosen, Harvey
openaire   +2 more sources