Results 121 to 130 of about 59,200 (224)

Opioids in breast cancer: Between analgesia and modulation of tumour progression

British Journal of Pharmacology, EarlyView.
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun, Anna Tankiewicz‐Kwedlo, Dariusz Pawlak   +2 more
wiley   +1 more source

Bacillus spore probiotics for alleviating functional constipation in children: a randomized, double-blind, placebo-controlled trial. [PDF]

Commun Med (Lond)
Nguyen HTL, Hoang HT, Le DP, Duong TQ, Vuong NTH, Truong MT, Nguyen HT, Nguyen AH, Pham TD, Nguyen ATV.   +9 more
europepmc   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, EarlyView.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source

Management of Childhood Functional Constipation [PDF]

Journal of Pediatric Health Care, 2018
openaire   +2 more sources

Functional constipation in children

, 2020
Functionele obstipatie is een veelvoorkomend chronisch probleem op de kinderleeftijd. Dit proefschrift is gericht op het onderzoeken van het meest optimale beleid voor kinderen met functionele obstipatie, en bespreekt nieuwe inzichten in de onderliggende oorzaak; diagnostische en therapeutische strategieën voor kinderen met (therapieresistente ...
openaire   +2 more sources

L‐VISP: LSTM Visualization for Interpretable Symptom Prediction in Patient Cohorts

Computer Graphics Forum, EarlyView.
L‐VISP is a human‐machine solution that uses visual analytics for LSTM modelling in clinical research. L‐VISP uses custom visual encodings to make multiple LSTM variants interpretable, supporting a full range of analysis, from understanding model operations and evaluating performance to interpreting results in a clinical context.
C. Floricel, Y. Wang, A. Wentzel, C. D. Fuller, G. E. Marai, M. E. Papka, G. Canahuate   +6 more
wiley   +1 more source

Research progress and controversies in the treatment of functional constipation-related depression with probiotics and prebiotics: a narrative review. [PDF]

Front Pharmacol
Dai Q, Duan Z, Fang C, Chen R.
europepmc   +1 more source

Evidence‐ and consensus‐based guideline on lichen sclerosus

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary The German‐language, consensus‐ and evidence‐based S3 guideline on lichen sclerosus (LS) was developed based on the European “EuroGuiDerm Guideline on lichen sclerosus” under the leadership of the German Dermatological Society (DDG) and the German Society for Gynecology and Obstetrics (DGGG).
Gudula Kirtschig, Linn Woelber, Andreas Günthert, Karl Becker, Alexandra Ciresa‐König, Bettina Fischer, Susanne Fricke‐Otto, Claudia Günther, Christine Hirchenhain, Narayani Helga Köllmann, Alexander Kreuter, Bartosz Malisiewicz, Felix Neis, Dan mon O'Dey, Hagen Ott, Martin Promm, Regina Renner, Anne‐Rose Schardt, Ines Schweizer, Raimund Stein, Jan Ter‐Nedden, Gerda Trutnovsky, Agnes Wand, Gerhard Weyandt, Ricardo N. Werner, Maria Kinberger   +25 more
wiley   +1 more source

Prevalence of Functional Constipation in Children with Down Syndrome: A Study Conducted at a General Pediatrics Service. [PDF]

Biomedicines
Pereira AMDC, Shin C, Henrique Parenti AB, Carvalho MA, Fonseca CRB.   +4 more
europepmc   +1 more source

<i>Bifidobacterium adolescentis</i> Strengthens Gut Barrier in Post-Voyage Functional Constipation. [PDF]

Int J Mol Sci
Zhao H, Wang H, Zhao X, Song Y, Liang D, Ma Y, Xu Z.   +6 more
europepmc   +1 more source