Results 241 to 250 of about 112,346 (350)

Effect of Linaclotide on Colonic Motility Assessed With Intraluminal Colonic High‐Resolution Manometry in Healthy Subjects. An Acute, Open Label, Randomized, Crossover, Reader‐Blinded Study

open access: yesNeurogastroenterology &Motility, EarlyView.
Our study showed that, in healthy controls, acute administration of linaclotide increased the total number of long‐distance propagating and the pre‐prandial pancolonic pressurizations. Further studies need to address whether the observed effects are directly or indirectly mediated by the mechanism of action of this useful medication to treat chronic ...
Christian Lambiase   +7 more
wiley   +1 more source

Sex‐Based Differences in Noncommunicable Diseases in Older Adults: Raising the Profile of Older Females

open access: yes
Journal of the American Geriatrics Society, EarlyView.
Aathmika Nandan   +2 more
wiley   +1 more source

Altered peripheral CRY1 gene expression may contribute to both organic and functional gastrointestinal disease

open access: yesExperimental Physiology, EarlyView.
ABSTRACT Gastrointestinal conditions such as irritable bowel syndrome (IBS) and inflammatory bowel diseases (IBD) are characterized by alterations in physiological and immune functions. Given the circadian clock influences gastrointestinal physiology and immunity, we hypothesized that the peripheral circadian clock is altered in these patients and ...
Sophie Fowler   +12 more
wiley   +1 more source

High Score of ELST‐Blue in Endoscopic Ultrasonography Strain Elastography May Provide a High Risk Group of Early Chronic Pancreatitis with the Reduction of Apolipoprotein A2‐i Index

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Background To evaluate the usefulness of the ELST‐blue score to explore its potential application in identifying high‐risk groups for early chronic pancreatitis (ECP) through reflecting on pancreatic elasticity and the reduction of pancreatic function, and we tried to demonstrate whether the ELST‐blue score was significantly associated with ...
Ken Nakamura   +17 more
wiley   +1 more source

Metabolomics Insights into Gut Microbiota and Functional Constipation. [PDF]

open access: yesMetabolites
Zheng F   +8 more
europepmc   +1 more source

Redefining the Treatment Landscape in Gastroparesis: A Clinical Review of Gastric Peroral Endoscopic Myotomy Outcomes and Therapeutic Integration

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Gastroparesis is a chronic gastric motility disorder marked by delayed gastric emptying in the absence of mechanical obstruction. For patients with symptoms refractory to medical and dietary therapy, Gastric Peroral Endoscopic Myotomy (G‐POEM) has emerged as a minimally invasive, pylorus‐targeted intervention that directly addresses pyloric ...
Kobina Essilfie‐Quaye   +6 more
wiley   +1 more source

[Functional constipation].

open access: yesRevista de gastroenterologia de Mexico, 2006
openaire   +1 more source

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