Results 261 to 270 of about 4,566,680 (308)

A Review of the Mechanisms of Action of the Herbal Medicine, STW 5‐II, Underlying Its Efficacy in Disorders of Gut–Brain Interaction

open access: yesNeurogastroenterology &Motility, EarlyView.
The pathophysiology of functional dyspepsia and irritable bowel syndrome includes altered motility, secretion, sensitivity to sensory signals, impaired epithelial barrier function, inflammation, and gut dysbiosis. The phytomedicine, STW 5‐II, represents a multi‐targeted approach, addressing these pathophysiologies.
Anita Annaházi   +6 more
wiley   +1 more source

Validation of the PROMIS Global Physical and Mental Health Scale for Gastrointestinal Disorders: A Large‐Scale Cross‐Sectional Survey

open access: yesNeurogastroenterology &Motility, EarlyView.
The 4‐item revised version of the Hays model from the PROMIS Global Health Scale exhibits stronger psychometric properties than the original model. This ultra‐brief assessment tool is a reliable measure for evaluating quality of life in both gastrointestinal and non‐gastrointestinal cohorts.
Pragalathan Apputhurai   +5 more
wiley   +1 more source

Long‐Term Clinical and Physiological Outcomes in Patients Treated Non‐Surgically for Anorectal Malformations

open access: yesNeurogastroenterology &Motility, EarlyView.
The long‐term anorectal outcomes of non‐surgically treated patients diagnosed with minor types of ARM seem optimal. Most of these patients experience no constipation or fecal incontinence; some experience constipation and relatively seldom fecal incontinence. Furthermore, most patients possess all the known fecal continence mechanisms.
Venla E. C. den Hollander   +3 more
wiley   +1 more source

Abnormal Homeostasis in the Redox State and Related Signaling Pathways, in Irritable Bowel Syndrome

open access: yesNeurogastroenterology &Motility, EarlyView.
There is higher oxidative stress and higher expression of transcription factor NF‐κB and the gp91 subunit of NADPH oxidase in IBS, with lower antioxidant regulator Nrf2. There are no differences in the IBS subtypes; however, in IBS‐C, malondialdehyde correlated with IL‐4, and TNF‐α with IL‐10, suggesting an interleukin‐mediated anti low‐grade ...
A. S. Morales‐Guzmán   +7 more
wiley   +1 more source

Possible Role of Butyric Acid in Long‐Term Symptom Relief in Irritable Bowel Syndrome Patients Following Fecal Microbiota Transplantation

open access: yesNeurogastroenterology &Motility, EarlyView.
Fecal butyric acid levels increased in IBS patients at 2 and 3 years after FMT and were inverse correlation with both IBS symptoms and fatigue suggesting that butyric acid contributes to the long‐term improvement seen after FMT. ABSTRACT Background We previously found that the fecal levels of short‐chain fatty acids (SCFAs) changed in irritable bowel ...
Magdy El‐Salhy   +4 more
wiley   +1 more source

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