Results 271 to 280 of about 112,346 (350)

Functional constipation in Chinese infants: disruptions in gut microbiota and urinary metabolome revealed by a cross-sectional analysis. [PDF]

Front Microbiol
Zhao H, Lu X, Lou H, Ye Y, Ye H, Li W, Long Z, Zhang X, Wu J, Wang J.   +9 more
europepmc   +1 more source

Development and Testing of an Owner‐Reported Outcome Measure of Clinical Signs and Quality of Life in Dogs Treated With Chemotherapy

Veterinary and Comparative Oncology, Volume 24, Issue 1, Page 80-94, March 2026.
ABSTRACT Cancer is a leading cause of mortality in older dogs. Despite the prevalence of chemotherapy in canine oncology, a good understanding of owners' observations of side effects and clinical signs in real time is still lacking. Owners' perceptions and reporting of clinical signs play an important role in monitoring a dog's condition during ...
Jenny Harris, Katie Sutton, Quentin Fournier, Jo Armes, Emma Ream, Nicholas Bacon   +5 more
wiley   +1 more source

Piezo knockdown reduces 5‑hydroxytryptamine release from enterochromaffin cells and exacerbates intestinal dyskinesia in mice with functional constipation. [PDF]

Int J Mol Med
Yan X, Ma P, Wang W, Zeng W, Li Y, Hou Y, Ye J, Zheng Q, Zhang W, Yao J, Li Y.   +10 more
europepmc   +1 more source

Iptacopan for Immune Thrombocytopenia and Cold Agglutinin Disease: A Global Phase 2 Basket Clinical Trial

American Journal of Hematology, Volume 101, Issue 2, Page 242-254, February 2026.
ABSTRACT Iptacopan is a first‐in‐class, oral, selective inhibitor of complement factor B that has demonstrated positive efficacy across several complement‐driven diseases. Here we evaluate the efficacy and safety of iptacopan monotherapy in adult patients with primary immune thrombocytopenia (ITP) and primary cold agglutinin disease (CAD). We performed
Alexander Röth, Wilma Barcellini, Christine Ademokun, Junho Jang, Maria Luisa Lozano, David Valcarcel Ferreiras, Cristina Pascual‐Izquierdo, Shripad Chitnis, Sofiya Matviykiv, Alessandra Vitaliti, Chi Chen, Vasiliki Katsanou, Raghav Chawla, Hanny Al‐Samkari   +13 more
wiley   +1 more source

Correction: Clinical efficacy of non-pharmacological treatment of functional constipation: a systematic review and network meta-analysis. [PDF]

Front Cell Infect Microbiol
Tan S, Peng C, Lin X, Peng C, Yang Y, Liu S, Huang L, Bian Y, Li Y, Xu C.   +9 more
europepmc   +1 more source

An OGT Missense Variant With Impaired Enzyme Activity in a Child With Severe Developmental Delay and Hepatoblastoma

American Journal of Medical Genetics Part A, Volume 200, Issue 2, Page 502-510, February 2026.
ABSTRACT O‐GlcNAc transferase (OGT) and its antagonist O‐GlcNAcase (OGA) regulate protein O‐GlcNAcylation, a highly conserved post‐translational modification involved in metabolic sensing. Pathogenic variants in the OGT gene cause an X‐linked congenital disorder of glycosylation (OGT‐CDG) presenting developmental delay, hypotonia, intellectual ...
Alfonso Manuel D'Alessio, Huijie Yuan, Leandro Raul Soria, Sara Basse Hansen, Iolanda Boffa, Paola Arena, Benedetta Attianese, Maureen. O'Sullivan, Noelle Cullinan, Lewis Pang, Daan Marinus Ferdinand van Aalten, Nicola Brunetti‐Pierri, Sally Ann Lynch   +12 more
wiley   +1 more source

Toilets unblocked : A literature review of school toilets [PDF]

, 2013
Burton, Sarah
core  

Emergency Laparotomy for Abdominal Compartment Syndrome in a Child due to Chronic Functional Constipation. [PDF]

Case Rep Pediatr
Velaoras K, Pantalos G, Plataras C, Alexandrou I, Mene J, Filos K, Chatterjee A, Nikolinakos P, Zavras N.   +8 more
europepmc   +1 more source

Urinary tract infection‐related delirium in Alzheimer's disease and related dementias: Clinical challenges and translational opportunities

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract Alzheimer's disease and related dementias (ADRD) affects millions of patients worldwide and is a leading cause of morbidity in older adults. Patients with ADRD are particularly susceptible to developing urinary tract infection (UTI) and UTI‐related delirium, creating a self‐perpetuating cycle in which ADRD increases vulnerability to infection ...
Sarah Kim, Sarah Kremen, Itai Danovitch, Shouri Lahiri   +3 more
wiley   +1 more source

Inulin-induced improvements on bowel habit and gut microbiota in adults with functional constipation: findings of a randomized, double-blind, placebo-controlled study. [PDF]

BMC Gastroenterol
Puhlmann ML, Wegh CAM, van der Zalm SCC, Dam V, Doolan A, Meyer D, Belzer C, Vaughan EE, Benninga MA, Smidt H.   +9 more
europepmc   +1 more source