Mechanism‐Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy
Advanced Science, EarlyView.MISPOP integrates ensemble learning with membrane‐active physicochemical priors to identify Dermaseptin‐S9, a natural oncolytic peptide that disrupts tumor membranes, triggers immunogenic cell death, and shows strong antitumor activity. The study illustrates a mechanism‐informed route from peptide sequence data to cancer immunotherapy leads.
Wen Zhang +11 more
wiley +1 more source
Editorial: Resources for developmental ecological psychology: organicism, epigenetics, relational development, dynamic systems. [PDF]
Front PsycholSzokolszky A +3 more
europepmc +1 more source
Application of Acceptance and Commitment Therapy (ACT) in Hospice and Palliative Care Settings. [PDF]
J Hosp Palliat Care, 2023 Park SY.
europepmc +1 more source
V2CTx MXene as a Sacrificial Promoter for NiFe Catalyst for Anion Exchange Membrane Electrolyzers
Advanced Science, EarlyView.These findings demonstrate that V2CTx functions beyond passive conductive support as an active electronic participant whose structural legacy sustains durable performance even after vanadium leaching in Anion Exchange Membrane (AEM) Electrolysers. ABSTRACT Nickel‐iron layered double hydroxides (NiFe‐LDH) show excellent activity, their poor conductivity
Bastian Schmiedecke +12 more
wiley +1 more source
Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing
Advanced Science, EarlyView.Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley +1 more source
Through the extended evolutionary meta-model, and what ACT found there: ACT as a process-based therapy. [PDF]
J Contextual Behav SciOng CW +4 more
europepmc +1 more source
Quantum Photothermal Self‐Monitoring Fiber Probes for In Vivo Photothermal Therapy
Advanced Science, EarlyView.A miniaturized quantum photothermal fiber probe based on a metal/polymer/glass composite optoelectronic fiber that simultaneously guides lightwave and microwave was developed for the first time. The probe achieves enhanced photothermal conversion (13°C/mW, 25°C–120°C range) while providing real‐time self‐monitoring with 0.2°C thermal resolution at the ...
Wanjun Li +12 more
wiley +1 more source
The social brain in the classroom: insights from the SELF study on neural correlates of adolescent motivation, belonging, and learning. [PDF]
Front Hum NeurosciRaufelder D, Hoferichter F.
europepmc +1 more source
Advanced Science, EarlyView.Pseudorabies virus (PRV), an emerging zoonotic α‐herpesvirus, causes life‐threatening human encephalitis. We identified a broad‐spectrum neutralizing antibody 6F7 targeting PRV gD. It blocks gD‐Nectin‐1 binding and membrane fusion, inhibiting replication across all PRV variants, representing a promising candidate for anti‐PRV therapy.
Yue Sun +11 more
wiley +1 more source
An Intervention Based on Acceptance and Commitment Therapy for Childhood Separation Anxiety: A Case Study. [PDF]
Behav Sci (Basel)Lobato D +3 more
europepmc +1 more source