LorDist: a novel method for calculating the distance based on functional data analysis with application to longitudinal microbial data. [PDF]
Qi X +7 more
europepmc +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Healthcare Expenditure and COVID-19 in Europe: Correlation, Entropy, and Functional Data Analysis-Based Prediction of Hospitalizations and ICU Admissions. [PDF]
Hęćka P, Ejsmont W, Biernacki M.
europepmc +1 more source
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Historical precipitation and flood damage in Japan: functional data analysis and evaluation of models. [PDF]
Wakai A +4 more
europepmc +1 more source
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Correction: Historical precipitation and flood damage in Japan: Functional data analysis and evaluation of models. [PDF]
Wakai A +4 more
europepmc +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Bayesian covariance regression in functional data analysis with applications to functional brain imaging. [PDF]
Shamshoian J +4 more
europepmc +1 more source
Characterizing Neurocardiovascular Responses to an Active Stand Test in Older Women: A Pilot Study Using Functional Data Analysis. [PDF]
Xue F, Romero-Ortuno R.
europepmc +1 more source

