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Longitudinal Functional Data Analysis [PDF]

Stat, 2015
We consider analysis of dependent functional data that are correlated because of a longitudinal-based design: each subject is observed at repeated time visits and for each visit we record a functional variable.
Park, So Young, Staicu, Ana-Maria
core   +3 more sources

Functional data analysis with increasing number of projections [PDF]

, 2013
Functional principal components (FPC's) provide the most important and most extensively used tool for dimension reduction and inference for functional data.
Stefan Fremdt, Lajos Horváth, Piotr Kokoszka, Josef Steinebach   +3 more
openalex   +5 more sources

Bayesian Functional Data Analysis Using WinBUGS [PDF]

Journal of Statistical Software, 2010
We provide user friendly software for Bayesian analysis of functional data models using WinBUGS 1.4. The excellent properties of Bayesian analysis in this context are due to: (1) dimensionality reduction, which leads to low dimensional projection bases; (
Ciprian M. Crainiceanu, A. Jeffrey Goldsmith   +1 more
doaj   +1 more source

Semi-automated thrombin dynamics applying the ST Genesia thrombin generation assay

Frontiers in Cardiovascular Medicine, 2022
BackgroundThe haemostatic balance is an equilibrium of pro- and anticoagulant factors that work synergistically to prevent bleeding and thrombosis.
Audrey Carlo, Qiuting Yan, Qiuting Yan, Hugo Ten Cate, Romy De Laat-Kremers, Romy De Laat-Kremers, Bas De Laat, Bas De Laat, Marisa Ninivaggi   +8 more
doaj   +1 more source

Assessing the individual roles of FII, FV, and FX activity in the thrombin generation process

Frontiers in Cardiovascular Medicine, 2022
Thrombin generation (TG) is known as a physiological approach to assess the hemostatic function. Although it correlates well with thrombosis and bleeding, in the current setup it is not sensitive to the effects of fluctuations in single coagulation ...
Cuicui Bai, Cuicui Bai, Joke Konings, Joke Konings, Marisa Ninivaggi, Marcus Lancé, Bas de Laat, Bas de Laat, Romy de Laat-Kremers   +8 more
doaj   +1 more source

Tailoring the effect of antithrombin-targeting therapy in haemophilia A using in silico thrombin generation

Scientific Reports, 2021
Factor (F) VIII deficiency causes bleeding in haemophilia A patients because of the reduced formation of procoagulant enzyme thrombin, which is needed to make the blood clot.
Romy M. W. de Laat-Kremers, Marisa Ninivaggi, Iris van Moort, Moniek de Maat, Bas de Laat   +4 more
doaj   +1 more source

Coagulation parameters predict COVID-19-related thrombosis in a neural network with a positive predictive value of 98%

Frontiers in Immunology, 2022
Thrombosis is a major clinical complication of COVID-19 infection. COVID-19 patients show changes in coagulation factors that indicate an important role for the coagulation system in the pathogenesis of COVID-19.
Romy de Laat-Kremers, Raf De Jongh, Raf De Jongh, Marisa Ninivaggi, Aernoud Fiolet, Rob Fijnheer, Jasper Remijn, Bas de Laat, Bas de Laat   +8 more
doaj   +1 more source

Abacavir use is associated with increased prothrombin conversion

Frontiers in Immunology, 2023
There is ongoing debate as to whether abacavir (ABC) increases the risk for cardiovascular disease(CVD) in people living with HIV (PLHIV) and the mechanisms underlying this possible association.
Qiuting Yan, Qiuting Yan, Shengshi Huang, Shengshi Huang, Wouter van der Heijden, Marisa Ninivaggi, Lisa van de Wijer, Romy de Laat-Kremers, Andre J. Van der Ven, Bas de Laat, Bas de Laat, Quirijn de Mast   +11 more
doaj   +1 more source

Optimal Estimation of Large Functional and Longitudinal Data by Using Functional Linear Mixed Model

Mathematics, 2022
The estimation of large functional and longitudinal data, which refers to the estimation of mean function, estimation of covariance function, and prediction of individual trajectory, is one of the most challenging problems in the field of high ...
Mengfei Ran, Yihe Yang
doaj   +1 more source

Charge transfer and X-ray absorption investigations in aluminium and copper co-doped zinc oxide nanostructure for perovskite solar cell electrodes

Scientific Reports, 2023
This study explores influence of charge transfer and X-ray absorption characteristics in aluminum (Al) and copper (Cu) co-doped zinc oxide (ZnO) nanostructures for perovskite solar cell electrodes.
Mandeep Kaur, Sanjeev Gautam, Keun Hwa Chae, Wantana Klysubun, Navdeep Goyal   +4 more
doaj   +1 more source