Results 221 to 230 of about 67,156 (272)

Synthesis, Crystal Structure, and Transport in Ordered Vacancy Compound Hg₂SiTe₄. [PDF]

Inorg Chem
Porter CE, Qu J, Yox P, Berriodi T, Maughan AE, Ertekin E, Toberer ES.   +6 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Molecular hallmarks of neurodegeneration in polyglutamine spinocerebellar ataxias. [PDF]

Cell Death Dis
Nóbrega C, Marcelo A, Rajado AT, Conceição A, Estevam B, Matos CA, Brito DV, Afonso IT, Codêsso JM, Koppenol R, Costa RG, Afonso-Reis R, Paulino R, Moreira-Gomes T.   +13 more
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

TDP-43 dysfunction compromises UPF1-dependent mRNA metabolism in ALS. [PDF]

Neuron
Alessandrini F, Wright M, Kurosaki T, Perloff OS, Ngo M, Kofler JK, Donnelly CJ, Maquat LE, Kiskinis E.   +8 more
europepmc   +1 more source

Spatial transcriptomic characterization of the pathologic niche in a patient with pulmonary crystal-storing histiocytosis. [PDF]

Genes Dis
Chen Y, Huang Z, Wang G, Wu M, Chen X, Sun X, Gao L, Xie M.   +7 more
europepmc   +1 more source

Reframing TDP-43 in Alzheimer's disease: From co-pathology to neurovascular culprit. [PDF]

Alzheimers Dement
Di Donna MG, Motta C, Bonomi CG, Bernocchi F, Ricci F, Poli M, Koch G, Martorana A.   +7 more
europepmc   +1 more source

Protein fingerprints of brain-derived extracellular vesicles predict types of tau pathology. [PDF]

Alzheimers Res Ther
Espourteille J, Barve A, Zufferey V, Leroux E, Perbet R, Bégard S, Caillierez R, Maurage CA, Toni N, Buée L, Colin M, Richetin K.   +11 more
europepmc   +1 more source

Anti-TLR2 immunotherapy modulates neuron-to-oligodendrocyte propagation of α-synuclein in mouse and human models. [PDF]

Nat Commun
Bae EJ, Ham S, Jeong YW, Yang WS, Shin J, Lee WJ, Ahn WJ, Yoon YS, Lee HJ, Lee SH, Park SH, Lee SJ.   +11 more
europepmc   +1 more source