Results 241 to 250 of about 7,721,508 (349)

Genome-wide characterization of NRAMP metal transporters reveals functional diversity for heavy metal tolerance in Onobrychis viciifolia. [PDF]

BMC Genomics
Li D, Song Y, Shen L, Xue Y, Liu Y, Tian X, Liang X, Gai Y, Xiao H.   +8 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Tissue origin dictates functional diversity of BMSC-derived EVs in bone regeneration. [PDF]

Front Cell Dev Biol
Wang J, Hong J, Tian C, Zhao X, Xie Q, Li N, Zhang Y, Liu M, Zhang P, Xing H, Wang L, Wang X.   +11 more
europepmc   +1 more source

Anatomical, Physiological, and Functional Diversity of Adipose Tissue.

Cell Metabolism, 2018
Rachel K. Zwick, C. Guerrero-Juarez, V. Horsley, M. Plikus   +3 more
semanticscholar   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Expression and functional diversity of the glucagon-like peptide-1 receptor across tumor types. [PDF]

Discov Oncol
Alba MM, Lee WH, Lee JSH, Lu Z, Stiles B, Ligumsky H.   +5 more
europepmc   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

UPGG: expanding the taxonomic and functional diversity of the pig gut microbiome with an enhanced genome catalog. [PDF]

NPJ Biofilms Microbiomes
Liu S, Feng B, Zhang Z, Miao J, Lai X, Zhao W, Xie Q, Ye X, Cao C, Yu P, Sun J, Guo J, Wang Z, Wang Q, Zhang Z, Pan Y.   +15 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Tuberculosis susceptibility in genetically diverse mice reveals functional diversity of neutrophils. [PDF]

Elife
Ravesloot-Chavez MM, Van Dis E, Fox D, Anaya-Sanchez A, Espich S, Nguyenla XH, Rawal S, Samani H, Ballinger M, Thomas HF, Kotov DI, Vance RE, Nachman MW, Stanley SA.   +13 more
europepmc   +1 more source