Results 91 to 100 of about 10,296,479 (327)
On a type of exponential functional equation and its superstability in the sense of Ger [PDF]
, 2013 In this paper, we deal with a type exponential functional equation as follows $$f(xy)=f(x)^{g(y)},$$ where $f$ and $g$ are two real valued functions on a commutative semigroup.
Alimohammady, M. +2 more
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
On the Stability of a Functional Equation Associated with the Fibonacci Numbers
, 2014 We prove the Hyers-Ulam stability of the generalized Fibonacci functional equation , where and h are given functions.
C. Mortici, M. Rassias, Soon-Mo Jung
semanticscholar +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Convergence of iterates of pre-mean-type mappings
ESAIM: Proceedings and Surveys, 2014 Pre-mean in an interval I, being defined as a function M:I2 → I such that M(x,x) = x for x ∈ I,is an essential generalization of the mean.
Matkowski Janusz
doaj +1 more source
Approximation on the Quadratic Reciprocal Functional Equation
, 2014 The quadratic reciprocal functional equation is introduced. The Ulam stability problem for an -quadratic reciprocal mapping between nonzero real numbers is solved.
A. Bodaghi, Sang Og Kim
semanticscholar +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Eigenvalues and Functional Equations [PDF]
Proceedings of the American Mathematical Society, 1957 Abstract : The purpose of this paper was to illustrate how the techniques of the theory of dynamic programming may be used to convert a number of eigenvalue problems, where one is interested only in maximum or minimum values, into problems involving recurrence relations.
openaire +2 more sources