Results 101 to 110 of about 9,324,703 (377)
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
On the superstability of the cosine and sine type functional equations
Annales Universitatis Paedagogicae Cracoviensis: Studia Mathematica, 2016 In this paper, We study the superstablity problem of the cosine and sine type functional equations: f(xσ(y)a)+f(xya)=2f(x)f(y) and f(xσ(y)a)-f(xya)=2f(x)f(y), where f:S → C is a complex valued function; S is a semigroup; σ is an involution of
Fouad Lehlou +3 more
doaj +1 more source
Solution and Stability of the Multiquadratic Functional Equation
, 2013 We consider the multiquadratic functional equation. We establish its general solution and provide a characterization for this functional equation. Finally, we prove the Hyers-Ulam-Rassias stability of this functional equation.
Xiaopeng Zhao +2 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Qualitative Study for a Delay Quadratic Functional Integro-Differential Equation of Arbitrary (Fractional) Orders [PDF]
, 2022 A. M. A. El-Sayed +2 more
openalex +1 more source
Hyperstability of the Drygas Functional Equation
, 2013 We use the fixed point theorem for functional spaces to obtain the hyperstability result for the Drygas functional equation on a restricted domain. Namely, we show that a function satisfying the Drygas equation approximately must be exactly the solution ...
M. Piszczek, J. Szczawińska
semanticscholar +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Renormalization group functional equations
Physical Review D, 2011 Functional conjugation methods are used to analyze the global structure of various renormalization group trajectories, and to gain insight into the interplay between continuous and discrete rescaling. With minimal assumptions, the methods produce continuous flows from step-scaling functions, and lead to exact functional relations for the local flow
Curtright, Thomas L., Zachos, Cosmas K.
openaire +3 more sources
On a solution to a functional equation
, 2018 We offer a solution to a functional equation using properties of the Mellin transform. A new criteria for the Riemann Hypothesis is offered as an application of our main result, through a functional relationship with the Riemann xi ...
Patkowski, Alexander E
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source