Results 101 to 110 of about 1,776,451 (338)

Variants of the functional equation of Cauchy

open access: yesLietuvos Matematikos Rinkinys, 2004
In this paper solution of the Cauchy functional equation and variants of it are considered.
Juozas Mačys
doaj   +1 more source

On a Functional Equation of Ruijsenaars

open access: yesTheoretical and Mathematical Physics, 2002
We obtain the general solution of the functional equation introduced by Ruijsenaars guaranteeing the commutativity of n operators associated with the quantum Ruijsenaars-Schneider models.
Byatt-Smith, J. G. B., Braden, H. W.
openaire   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

On the superstability of the cosine and sine type functional equations

open access: yesAnnales Universitatis Paedagogicae Cracoviensis: Studia Mathematica, 2016
In this paper, We study the superstablity problem of the cosine and sine type functional equations: f(xσ(y)a)+f(xya)=2f(x)f(y) and f(xσ(y)a)-f(xya)=2f(x)f(y), where f:S → C is a complex valued function; S is a semigroup; σ is an involution of
Fouad Lehlou   +3 more
doaj   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Substitution Delone Sets

open access: yes, 2001
This paper addresses the problem of describing aperiodic discrete structures that have a self-similar or self-affine structure. Substitution Delone set families are families of Delone sets (X_1, ..., X_n) in R^d that satisfy an inflation functional ...
Jeffrey C. Lagarias   +3 more
core   +3 more sources

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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