Results 121 to 130 of about 8,944,209 (378)
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
ON THE PROBABILISTIC STABILITY OF THE MONOMIAL FUNCTIONAL EQUATION
, 2013 Using the fixed point method, we establish a generalized Ulam Hyers stability result for the monomial functional equation in the setting of complete random p-normed spaces.
C. Zaharia
semanticscholar +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
D'Alembert's functional equation on groups
, 2013 Given a (not necessarily unitary) character μ : G→ (C\{0}, ·) of a group G we find the solutions g : G→ C of the following version of d’Alembert’s functional equation g(xy) + μ(y)g(xy) = 2g(x)g(y), x, y ∈ G.
H. Stetkær
semanticscholar +1 more source
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
International Journal of Mathematics and Mathematical Sciences, 1986 In this series, this paper is devoted to the study of a functional equation connected with the characterization of weighted entropy and weighted entropy of degree β.
Pl. Kannappan, P. K. Sahoo
doaj +1 more source
On the conformal mapping of curvilinear angles. The functional equation 𝜙[𝑓(𝑥)]=𝑎₁𝜙(𝑥) [PDF]
, 1917 G. A. Pfeiffer
openalex +1 more source
On a functional equation of Bellman
Journal of Mathematical Analysis and Applications, 1978 where x > 0, fr
openaire +2 more sources
On the stability of an affine functional equation
, 2013 In this paper, we obtain the general solution and we prove the generalized Hyers-Ulam stability for an affine functional equation.
L. Cadariu, L. Gǎvruţa, P. Gǎvruţa
semanticscholar +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source