Results 251 to 260 of about 10,695,687 (313)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Publisher Correction: Succession of phytoplankton functional groups in a subtropical lake associated with rainfall patterns. [PDF]

Sci Rep
Li T, Zhang Y, Zhang L, Liu Z, Zhu J, Zhou Y, Yang JR.   +6 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Niche Differentiation Characteristics of Phytoplankton Functional Groups in Arid Regions of Northwest China Based on Machine Learning. [PDF]

Biology (Basel)
Yun L, Zi F, Qiu X, Liu Q, Zhang J, Yang L, Song Y, Chen S.   +7 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Developmental Toxicity of Photolithography-Relevant Per- and Polyfluoroalkyl Substances (PFAS) Reveals Concerns for Less-Studied Functional Groups. [PDF]

Environ Sci Technol
Cao Y, Smaili H, Shanks HQ, Tvermoes BE, Niu S, Chen R, Hukriede NA, Ng CA.   +7 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Catalyst poisoning influences from various functional groups of energy carriers towards electrochemical oxidation reactions on non-noble high-entropy alloy anodes in acidic media. [PDF]

Sci Technol Adv Mater
Tahawy R, Muflihah SA, Hara K, Ohto T, Tanimoto H, Li T, Abdelnabi M, Jeong S, Nishiuchi T, Kimizuka H, Aimon AH, Ito Y.   +11 more
europepmc   +1 more source

LINKER: <u>L</u>earning <u>In</u>teractions between Functional Groups and Residues with Chemical <u>K</u>nowledge-<u>E</u>nhanced <u>R</u>easoning and Explainability. [PDF]

J Chem Inf Model
Pham P, Nguyen VTD, Song K, Chen J, Hy TS.   +4 more
europepmc   +1 more source

Succession of phytoplankton functional groups in a subtropical lake associated with rainfall patterns. [PDF]

Sci Rep
Li T, Zhang Y, Zhang L, Liu Z, Zhu J, Zhou Y, Yang JR.   +6 more
europepmc   +1 more source