Results 51 to 60 of about 5,257,958 (296)

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine, Ofélie Trudeau‐Ferrin, Caroline Laverdière, Patrick Hamel, Rosanne Superstein, Bénédicte Koukoui, Carole Provost, Paul C. Nathan, Vijay Ramaswamy, Furqan Shaikh, Brenda Gallie, Ashwin Mallipatna, Stephanie Kletke, Helen Dimaras, Hallie Coltin   +14 more
wiley   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Phytoplankton scenario and microcystin in water during extreme drought in semiarid tropical water supplies, Northeastern Brazil

Brazilian Journal of Biology, 2019
The objective of this study was to characterize the limnological, microystin and phytoplankton community of five tropical eutrophic reservoirs located in the Brazilian northeastern semi-arid region, used for domestic use at the time of extreme drought ...
A. H. G. Rego, A. Rangel-Junior, I. A. S. Costa   +2 more
doaj   +1 more source

Relationships between Combustion Behavior in Air and the Chemical Structure of Bituminous Coal during Combustion Processes

Energies, 2022
The structural parameters of five bituminous coals were analyzed by using X-ray diffraction and attenuated total reflection–Fourier transform infrared spectroscopy.
Shuxing Qiu, Ramana G. Reddy, Xianyou Huang, Chen Yin, Shengfu Zhang   +4 more
doaj   +1 more source

Understanding β-Hydride Eliminations from Heteroatom Functional Groups [PDF]

, 2011
Using density functional theory, we investigated detailed aspects of the quintessential organometallic process, β-hydride elimination (BHE). In general, we find that most BHE processes from alkyl functional group β-atoms are facile, while BHE processes ...
Goddard, William A. III, Theofanis, Patrick L.   +1 more
core   +1 more source

Dissociation of structural and functional integrities of the motor system in amyotrophic lateral sclerosis and behavioral-variant frontotemporal dementia [PDF]

, 2016
Background and Purpose: This study investigated the structural and functional changes in the motor system in amyotrophic lateral sclerosis (ALS; n=25) and behavioral-variant fronto-temporal dementia (bvFTD; n=17) relative to healthy controls (n=37 ...
Bae, Jong Seok, Burrell, James, Ferguson, Michele, Hodges, John R., Hornberger, Michael, Kiernan, Matthew C., Mioshi, Eneida, Simon, Neil, Tan, Rachel, Vucic, Steve   +9 more
core   +2 more sources

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Perennial Grass and Native Wildflowers: A Synergistic Approach to Habitat Management

Insects, 2017
Marginal agricultural land provides opportunities to diversify landscapes by producing biomass for biofuel, and through floral provisioning that enhances arthropod-mediated ecosystem service delivery.
Shereen S. Xavier, Dawn M. Olson, Alisa W. Coffin, Timothy C. Strickland, Jason M. Schmidt   +4 more
doaj   +1 more source

Beyond the Hydro-Regime: Differential Regulation of Plant Functional Groups in Seasonal Ponds

Diversity, 2023
Plant community assembly can be influenced by many environmental factors. In seasonal wetlands, most studies focus on the considerable variation that occurs from the hydro-regime (patterns of inundation and desiccation).
Jasmine Rios, Melanie Dibbell, Emely Flores, Jamie M. Kneitel   +3 more
doaj   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source