Results 81 to 90 of about 107,051 (305)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Resonance identities for closed characteristics on compact star-shaped hypersurfaces in R-2n
, 2014 Resonance relations among periodic orbits on given energy hypersurfaces are very important for getting deeper understanding of the dynamics of the corresponding Hamiltonian systems.
Wang, Wei, Long, Yiming, Liu, Hui
core +1 more source
(De)Construction of Gendered Identities in ELT Materials: A Systemic Functional View
Forma y FunciónWith an ever-increasing abundance of English Language Teaching materials, there is always a need for research to unearth the possible gendered discourses in/around them.
Alireza Rasti
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
, 2011 Increased consumer and professional interest in healthy foods and beverages, coupled with recent advances in food science technology, have seen food-producing organisations create and market food products claiming to offer physiological benefits beyond ...
Johnson, Vanessa
core
On certain identities in theta functions [PDF]
Transactions of the American Mathematical Society, 1930 1. The purpose of this paper is to obtain certain identities in Jacobi's theta functions by a new method. This method may be outlined as follows. We consider two sets of elements S and Si, conceptually distinct, such that the elements of S are in one-to-one correspondence with the elements of S1.
openaire +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Functional Equations, Distributions and Approximate Identities
, 1990 The subject of this paper is the use of the theory of Schwartz distributions and approximate identities in studying the functional equationThe aj’s and b are complex-valued functions defined on a neighbourhood, U, of 0 in Rm, hj.
John A. Baker
core +1 more source
Finite BRST–antiBRST transformations in Lagrangian formalism
Physics Letters B, 2014 We continue the study of finite BRST–antiBRST transformations for general gauge theories in Lagrangian formalism initiated in [1], with a doublet λa, a=1,2, of anticommuting Grassmann parameters, and find an explicit Jacobian corresponding to this change
Pavel Yu. Moshin +1 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source