Results 41 to 50 of about 2,065,342 (284)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

ROI-Based Analysis of Functional Imaging Data [PDF]

, 2002
In this technical report, we present fMRI analysis techniques that test functional hypotheses at the region of interest (ROI) level. An SPM-compatible Matlab toolbox has been developed which allows the creation of subject-specific ROI masks based on ...
Ghosh, Satrajit, Guenther, Frank, Nieto-Castanon, Alfonso, Tourville, Jason   +3 more
core   +1 more source

Mapping the landscape: a bibliometric analysis of resting-state fMRI research on schizophrenia over the past 25 years

Schizophrenia
Schizophrenia, a multifaceted mental disorder characterized by disturbances in thought, perception, and emotion, has been extensively investigated through resting-state fMRI, uncovering changes in spontaneous brain activity among those affected. However,
Linhan Fu, Remilai Aximu, Guoshu Zhao, Yayuan Chen, Zuhao Sun, Hui Xue, Shaoying Wang, Nannan Zhang, Zhihui Zhang, Minghuan Lei, Ying Zhai, Jinglei Xu, Jie Sun, Juanwei Ma, Feng Liu   +14 more
doaj   +1 more source

Intestinal Microbiota and Vaccinations: A Systematic Review of the Literature

Vaccines
Background: Vaccination constitutes a low-cost, safe, and efficient public health measure that can help prevent the spread of infectious diseases and benefit the community.
Francesco Loddo, Pasqualina Laganà, Caterina Elisabetta Rizzo, Serena Maria Calderone, Bruno Romeo, Roberto Venuto, Daniele Maisano, Francesco Fedele, Raffaele Squeri, Alessandro Nicita, Antonio Nirta, Giovanni Genovese, Linda Bartucciotto, Cristina Genovese   +13 more
doaj   +1 more source

The variability of functional MRI brain signal increases in Alzheimer's disease at cardiorespiratory frequencies

Scientific Reports, 2020
Biomarkers sensitive to prodromal or early pathophysiological changes in Alzheimer’s disease (AD) symptoms could improve disease detection and enable timely interventions. Changes in brain hemodynamics may be associated with the main clinical AD symptoms.
Timo Tuovinen, Janne Kananen, Zalan Rajna, Johannes Lieslehto, Vesa Korhonen, Riikka Rytty, Heli Mattila, Niko Huotari, Lauri Raitamaa, Heta Helakari, Ahmed Abou Elseoud, Johanna Krüger, Pierre LeVan, Osmo Tervonen, Juergen Hennig, Anne M. Remes, Maiken Nedergaard, Vesa Kiviniemi   +17 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Learning and comparing functional connectomes across subjects [PDF]

, 2013
Functional connectomes capture brain interactions via synchronized fluctuations in the functional magnetic resonance imaging signal. If measured during rest, they map the intrinsic functional architecture of the brain.
Craddock, R. C., Varoquaux, Gaël
core   +4 more sources

Exploring functional dysconnectivity in schizophrenia: alterations in eigenvector centrality mapping and insights into related genes from transcriptional profiles

Schizophrenia
Schizophrenia is a mental health disorder characterized by functional dysconnectivity. Eigenvector centrality mapping (ECM) has been employed to investigate alterations in functional connectivity in schizophrenia, yet the results lack consistency, and ...
Yuan Ji, Mengjing Cai, Yujing Zhou, Juanwei Ma, Yijing Zhang, Zhihui Zhang, Jiaxuan Zhao, Ying Wang, Yurong Jiang, Ying Zhai, Jinglei Xu, Minghuan Lei, Qiang Xu, Huaigui Liu, Feng Liu   +14 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

A Pneumatically Actuated Manipulandum for Neuromotor Control Research [PDF]

, 2002
Functional magnetic resonance imaging (fMRI) techniques have great potential for identifying which neural structures are involved in the control of goal-directed reaching movements.
Ropella, Kristina M., Scheidt, Robert A., Suminski, Aaron J   +2 more
core   +1 more source