Results 101 to 110 of about 59,835 (302)

CORTICAL ASYMMETRIES DURING HAND LATERALITY TASK VARY WITH HAND LATERALITY: A FMRI STUDY IN 295 PARTICIPANTS.

Frontiers in Human Neuroscience, 2016
The aim of this study was to characterize, using fMRI, the functional asymmetries of Hand Laterality Task (HLT) in a sample of 295 participants balanced for handedness.
Emmanuel Mellet, Bernard Mazoyer, Gaelle Leroux, Marc Joliot, Nathalie Tzourio-Mazoyer   +4 more
doaj   +1 more source

Insecure attachment during infancy predicts greater amygdala volumes in early adulthood [PDF]

, 2014
Background The quality of the early environment is hypothesized to be an influence on morphological development in key neural areas related to affective responding, but direct evidence to support this possibility is limited.
Ahnert, Ainsworth, Baare, Barros-Loscertales, Baur, Bowlby, Brain Development Cooperative Group, Caetano, Caldji, Campbell, Cassidy, Chen, Cox, Dedovic, Erp, Fearon, Fox, Free, Gerritsen, Groh, Gunnar, Halligan, Hertsgaard, Holmes, Huang, Huot, Kaufman, Ladd, Ladouceur, Luby, Lupien, Lupien, MacMaster, MacMillan, Main, McCrory, Meaney, Mehta, Morey, Moutsiana, Munn, Murray, Murray, Murray, Ono, Pannekoek, Qin, Raineki, Rao, Rao, Romanczuk-Seiferth, Rorden, Rosso, Smith, Smith, Spangler, Spitzer, Spitzer, Tottenham, Videbech, Whalen, Wolff, Woolrich   +62 more
core   +4 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Altered functional connectivity differs in stroke survivors with impaired touch sensation following left and right hemisphere lesions

NeuroImage: Clinical, 2018
One in two survivors experience impairment in touch sensation after stroke. The nature of this impairment is likely associated with changes associated with the functional somatosensory network of the brain; however few studies have examined this.
Peter Goodin, Gemma Lamp, Rishma Vidyasagar, David McArdle, Rüdiger J. Seitz, Leeanne M. Carey   +5 more
doaj   +1 more source

Cognitive Ability and Hemispheric Indecision - Two Surpluses and a Deficit [PDF]

This paper re-examines a finding by Crow et al. (1998) showing that equal skill of right and left hands – hemispheric indecision - is associated with deficits in cognitive ability. This is consistent with the idea that failure to develop dominance of one
Kevin Denny
core   +3 more sources

Laterality of Eye Use by Bottlenose (Tursiops truncatus) and Rough-toothed (Steno bredanensis) Dolphins While Viewing Predictable and Unpredictable Stimuli [PDF]

, 2020
Laterality of eye use has been increasingly studied in cetaceans. Research supports that many cetacean species keep prey on the right side while feeding and preferentially view unfamiliar objects with the right eye.
de Vere, Amber J., Lilley, Malin K., Yeater, Deirdre B.   +2 more
core   +2 more sources

DUAL FUNCTIONALITY IN LATER LIFE

Innovation in Aging, 2022
Abstract Longevity and quality of life are core interests in gerontology, but debate has ensued as scholars have sought to integrate the two. I propose the concept of dual functionality to examine how humans reach advanced ages while maintaining both physical and cognitive function.
openaire   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Lateralization of Temporal Lobe Epilepsy based on Resting-State Functional Magnetic Resonance Imaging and Machine Learning

Frontiers in Neurology, 2015
Lateralization of temporal lobe epilepsy (TLE) is critical for successful outcome of surgery to relieve seizures. TLE affects brain regions beyond the temporal lobes and has been associated with aberrant brain networks, based on evidence from functional ...
Zhengyi eYang, Jeiran eChoupan, David eReutens, Julia eHocking   +3 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source