Results 31 to 40 of about 37,182 (262)

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Hierarchical cortical gradients in somatosensory processing

NeuroImage, 2020
Sensory information is processed in the visual cortex in distinct streams of different anatomical and functional properties. A comparable organizational principle has also been proposed to underlie auditory processing. This raises the question of whether
Noam Saadon-Grosman, Shahar Arzy, Yonatan Loewenstein   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Heritability of language laterality assessed by functional transcranial Doppler ultrasound: a twin study [version 2; peer review: 1 approved, 2 approved with reservations]

Wellcome Open Research, 2020
Background: Prior studies have estimated heritability of around 0.25 for the trait of handedness, with studies of structural brain asymmetry giving estimates in a similar or lower range.
Dorothy V.M. Bishop, Timothy C. Bates
doaj   +1 more source

Effects of caller characteristics on auditory laterality in an early primate (Microcebus murinus). [PDF]

PLoS ONE, 2010
BACKGROUND: Auditory laterality is suggested to be characterized by a left hemisphere dominance for the processing of conspecific communication.
Lisette M C Leliveld, Marina Scheumann, Elke Zimmermann   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Measurement of language laterality using functional transcranial Doppler ultrasound: a comparison of different tasks [version 2; referees: 2 approved]

Wellcome Open Research, 2018
Background: Relative blood flow in the two middle cerebral arteries can be measured using functional transcranial Doppler sonography (fTCD) to give an index of lateralisation as participants perform a specific task.
Zoe V.J. Woodhead, Holly A. Rutherford, Dorothy V.M. Bishop   +2 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The Association Between Laterality and Stroke Severity: A Cross‐Sectional Study

Health Science Reports
Background and Aim Handedness is a manifestation of cerebral lateralization that has been implicated in various neurological and neurodevelopmental conditions.
Imen Ezzouch, Riadh Dahmen, Kaouther Mejri, Liwa Masmoudi, Saoussen Daoued, Dalia Elleuch, Sana Ben Amor, Mariem Dammak, Chokri Mhiri, Haitham Jahrami, Achraf Ammar, Khaled Trabelsi, Mohamed Jarraya   +12 more
doaj   +1 more source