Acute loss of mitral annular dynamics predicts development of functional mitral regurgitation after myocardial infarction in a swine model. [PDF]
Kikuchi Y +8 more
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Between Scylla and Charybdis in atrial functional mitral regurgitation. [PDF]
Denti P.
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Machine-learning phenotyping of patients with functional mitral regurgitation undergoing transcatheter edge-to-edge repair: the MITRA-AI study. [PDF]
D'Ascenzo F +40 more
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Commentator Discussion: Acute loss of mitral annular dynamics predicts development of functional mitral regurgitation after myocardial infarction in a swine model. [PDF]
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Functional mitral regurgitation
Current Opinion in Cardiology, 2020Purpose of review Functional mitral regurgitation (FMR) is a complex condition in which significant mitral regurgitation coexist with cardiomyopathy and heart failure and carries an increased risk for associated morbidity and mortality.
Federico M, Asch, Diego, Medvedofsky
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Functional Mitral Regurgitation
Cardiology in Review, 2010Functional mitral regurgitation (MR) is a common clinical entity which will likely increase in the future due to predicted demographic changes. It is also associated with poor long-term survival. The anatomic structure of the mitral valve apparatus is complex and consists of several components, each of which can be affected by a variety of diseases ...
Jan D, Schmitto +5 more
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Functional Mitral Regurgitation
Cardiology in Review, 2018Functional mitral regurgitation (FMR) is common in patients with heart failure and portends a poor prognosis. The etiology is secondary to nonischemic or ischemic (postmyocardial infarction) adverse remodeling. Treatment includes guideline-directed medical therapy, cardiac resynchronization therapy, and in some cases, surgical repair or replacement ...
Lowie M R, Van Assche, Mark J, Ricciardi
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Medical Therapy for Functional Mitral Regurgitation
Circulation: Heart Failure, 2022Functional mitral regurgitation (FMR) can be broadly categorized into 2 main groups: ventricular and atrial, which often coexist. The former is secondary to left ventricular remodeling usually in the setting of heart failure with reduced ejection fraction or less frequently due to ischemic papillary muscle remodeling.
Assi Milwidsky +3 more
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Ischemic (Functional) Mitral Regurgitation
Cardiology Clinics, 2013Mitral regurgitation (MR) is a frequent complication of myocardial infarction and coronary artery disease that is associated with adverse prognosis. The main mechanism of ischemic MR relates to distortion of the spatial relationships between the mitral valve and papillary muscles secondary to ventricular remodeling.
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The management of functional mitral regurgitation
Current Cardiology Reports, 2007Mitral regurgitation (MR) may be classified into two major categories: primary and secondary (functional). In primary MR, disease of the valve itself (eg, myxomatous degeneration, rheumatic disease) causes valve incompetence, producing left ventricular (LV) volume overload.
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