Results 71 to 80 of about 26,195 (192)

Unveiling New Insights: Reinterpreting DES Mutation, p.Arg383His, Through a Study of an Iranian Family With Isolated Hypertrophic Cardiomyopathy, Implication for Phenotype–Genotype Correlation Analysis

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Desmin, a crucial intermediate filament in muscle cells, maintains structural integrity in cardiac muscle and provides stability to striated muscle cells. Mutations in the DES gene lead to desminopathies, causing diverse cardiac and skeletal myopathies.
Saeideh Kavousi, Farzad Kamali, Bahareh Rabbani, Mehrdad Behmanesh, Nejat Mahdieh, Mehrdad Noruzinia   +5 more
wiley   +1 more source

Mechanisms and pathophysiology of mitral valve regurgitation

MAMC Journal of Medical Sciences, 2015
The mitral valve (MV) is a sophisticated natural engineering marvel. The MV requires coordinated action of all its interrelated anatomical components: The MV leaflets, the annulus, the left atrium, the tendinous chords and the papillary muscles with its ...
Praveen Kumar Neema
doaj   +1 more source

Evidence‐Based Nursing Management During Mavacamten Therapy in an 89‐Year‐Old Patient With Symptomatic Hypertrophic Obstructive Cardiomyopathy: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT In older patients receiving mavacamten, a reduction in NT‐proBNP levels may coexist with persistent severe LVOTO. Nurses should interpret this biomarker–echocardiography discordance as a safety signal and maintain structured cardiovascular surveillance rather than assuming treatment success based solely on biomarker improvement.
Feifei Wang
wiley   +1 more source

Simultaneous Heart–Kidney Transplantation for Ebstein's Anomaly: A Viable Treatment Option in Latin America

Clinical Case Reports, Volume 14, Issue 8, August 2026.
Chest x‐ray showing a typical presentation of Ebstein anomaly with severe cardiomegaly and a prominent right atrium silhouette. ABSTRACT Simultaneous heart–kidney transplantation is a viable and effective treatment option for patients with congenital heart disease and advanced chronic kidney disease when both conditions threaten survival.
Edgar García‐Cruz, Andrea Luna‐Hernández, Jesús Alberto Blanco‐Hernández, Jorge Sánchez‐Nieto, Stephanie Teresa Angulo‐Cruzado, Karla Alejandra Pupiales‐Dávila, Carla Domínguez‐Pereyra, Reyna Moreno‐Ruíz, Carlos Antonio Villegas‐Chávez, Antonio Jordán‐Ríos, Daniel Manzur‐Sandoval, Victor Alejandro Quiroz‐Martínez, Francisco Martín Baranda‐Tovar   +12 more
wiley   +1 more source

Failed MitraClip-procedure with pull out of the anterior leaflet

ScienceOpen Research, 2014
: MitraClip is an attractive and less invasive alternative to mitral valve surgery in serve mitral regurgitation in patients with moderate or severe risk for operation.
Michael Gross, Ursula Wilkenshoff, Susanne Rutschow   +2 more
doaj   +1 more source

Impact of Severe Postoperative Multi‐Organ Dysfunction on Long‐Term Outcomes After Modified Morrow Surgery

Clinical Cardiology, Volume 49, Issue 8, August 2026.
This retrospective cohort study (n = 380) demonstrates that severe postoperative multi‐organ dysfunction (SOFA Maximum ≥ 11) is a strong independent predictor of long‐term adverse outcomes after modified Morrow surgery. Incorporating the SOFA score into postoperative assessments helps identify high‐risk hypertrophic obstructive cardiomyopathy patients ...
Tong Wang, La Ta, Kui Zhang, Ran Dong, Yu Xiao, Jiayang Wang   +5 more
wiley   +1 more source

The Serotonin 2B (5‐HT2B) Receptor: A Narrative Review of Preclinical and Clinical Evidence on the Safety Considerations and Therapeutic Potential for the Treatment of Depression

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 345-356, August 2026.
Major depressive disorder (MDD) and treatment‐resistant depression (TRD) remain leading causes of disability, providing the impetus for receptor‐level treatment strategies beyond monoamine reuptake. The serotonin 5‐HT2B receptor (5‐HT2BR) is uniquely positioned at the interface of central‐antidepressant mechanisms and peripheral cardiac risks.
Gia Han Le, Sabrina Wong, Danica E. Johnson, Diana K. Orsini, Yang Jing Zheng, Kayla M. Teopiz, Christine E. Dri, Joshua D. Rosenblat, Roger S. McIntyre   +8 more
wiley   +1 more source

Technologies in minimally invasive treatment of severe mitral regurgitation

Cardiology Journal
Mitral valve regurgitation is the second most common valve defect in Europe among adults. Primary mitral regurgitation (MR) results from structural abnormalities of the valve apparatus (e.g., leaflet prolapse, chordae rupture), often due to myxomatous ...
Magdalena Synak, Marta Mazur, Kamil Marzec, Krzysztof Sanetra, Justyna Jankowska-Sanetra, Piotr P. Buszman, Paweł Kaźmierczak, Krzysztof Milewski, Witold Gerber   +8 more
doaj   +1 more source

Chronic valvular disease: correlation between clinical, electrocardiographic, radiographic and echocardiographic aspects in dogs Doença valvar crônica: correlação entre aspectos clínicos, eletrocardiográficos, radiográficos e ecocardiográficos em cães

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2005
Echocardiographic aspects of chronic mitral valvular disease were studied and compared to physical, radiographic and electrocardiographic aspects.
E.C. Soares, M.H.M.A. Larsson, R.J. Yamato   +2 more
doaj   +1 more source

Quantification of Tricuspid Valve Regurgitation With 2D and 4D‐Flow MRI: Comparison of Different Methods in Adult Patients With Ebstein's Anomaly

Journal of Magnetic Resonance Imaging, Volume 64, Issue 2, Page 515-523, August 2026.
ABSTRACT Background Ebstein's anomaly (EA) is a congenital heart disorder involving tricuspid valve dysplasia and right heart abnormalities resulting in severe tricuspid regurgitation (TR). Multiple techniques assess regurgitation severity, but their correlation with EA severity markers remains unclear. Purpose To compare MRI techniques for quantifying
Eric Buffle, Mathieu Albertini, Damian Craiem, Victor Waldmann, Francesca Pitocco, Laurence Iserin, Umit Gencer, Elie Mousseaux, Gilles Soulat   +8 more
wiley   +1 more source