Results 221 to 230 of about 2,526,308 (267)
Organoids for Metabolic Disease Modeling. [PDF]
J Inherit Metab DisArdisasmita AI +2 more
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Journal of Multivariate Analysis, 2020
The aim of this paper is to develop a new framework of surface functional models (SFM) for surface functional data which contains repeated observations in two domains (typically, time-location). The primary problem of interest is to investigate the relationship between a response and the two domains, where the numbers of observations in both domains ...
Chen, Ziqi, Hu, Jianhua, Zhu, Hongtu
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The aim of this paper is to develop a new framework of surface functional models (SFM) for surface functional data which contains repeated observations in two domains (typically, time-location). The primary problem of interest is to investigate the relationship between a response and the two domains, where the numbers of observations in both domains ...
Chen, Ziqi, Hu, Jianhua, Zhu, Hongtu
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Restricted function‐on‐function linear regression model
Biometrics, 2021AbstractThe usual function‐on‐function linear regression model depicts the association between functional variables in the whole rectangular region and the value of response curve at any point is influenced by the entire trajectory of the predictor curve.
Ruiyan Luo, Xin Qi
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Modeling mitochondrial function
American Journal of Physiology-Cell Physiology, 2006The mitochondrion represents a unique opportunity to apply mathematical modeling to a complex biological system. Understanding mitochondrial function and control is important since this organelle is critical in energy metabolism as well as playing key roles in biochemical synthesis, redox control/signaling, and apoptosis.
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Functional Mixed Effects Models
Biometrics, 2002Summary.In this article, a new class of functional models in which smoothing splines are used to model fixed effects as well as random effects is introduced. The linear mixed effects models are extended to non‐parametric mixed effects models by introducing functional random effects, which are modeled as realizations of zero‐mean stochastic processes ...
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Modelling ferroic functional elements
Journal of Computer-Aided Materials Design, 2007The present study aims at the modelling of an organic field-effect transistor generated by the self-assembly of field-sensitive molecules on the surfaces of ferroic oxides. Electronic-structure-based methods for the microscopic properties of the surface, the molecules, and the respective interactions are combined with classical modelling on the self ...
Gemming, S. +5 more
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Annual Review of Biomedical Engineering, 2003
▪ Abstract Computational models of the electrical and mechanical function of the heart are reviewed. These models attempt to explain the integrated function of the heart in terms of ventricular anatomy, the structure and material properties of myocardial tissue, the membrane ion channels, and calcium handling and myofilament mechanics of cardiac ...
Peter J, Hunter +2 more
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▪ Abstract Computational models of the electrical and mechanical function of the heart are reviewed. These models attempt to explain the integrated function of the heart in terms of ventricular anatomy, the structure and material properties of myocardial tissue, the membrane ion channels, and calcium handling and myofilament mechanics of cardiac ...
Peter J, Hunter +2 more
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Linear mixed function‐on‐function regression models
Biometrics, 2014SummaryWe develop a linear mixed regression model where both the response and the predictor are functions. Model parameters are estimated by maximizing the log likelihood via the ECME algorithm. The estimated variance parameters or covariance matrices are shown to be positive or positive definite at each iteration.
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Model of psychological functioning
Journal of Theoretical Biology, 1971Abstract A model of psychological functioning, based on the activity of individual neurons, is proposed. A method to identify general patterns of behavior is outlined. A biochemical mechanism to account for synaptic transmission and modification of behavior by experience is suggested and incorporated in a holographic model of memory.
D, Irving, P, Proctor
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Functional reasoning and functional modelling
IEEE Expert, 1991A car that will not start on a cold winter day and one that will not start on a hot summer day usually indicate two very different situations. When pressed to explain the difference, we would give a winter account-'Oil is more viscous in cold conditions, and that causes . .
J. Sticklen, W.E. Bond
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