Results 91 to 100 of about 4,562,205 (344)
Cholinergic Degeneration and Cognitive Function in Early GBA1‐Related Parkinson's Disease
Annals of Neurology, EarlyView.Objective The phenotype of patients with Parkinson's disease carrying GBA1 variants (GBA‐PD) suggest similarities to symptomatology associated with early cholinergic system degeneration. Therefore, this study aims to investigate the clinical features and the cholinergic innervation pattern in patients with early GBA‐PD versus those without the GBA1 ...
Sofie Slingerland +6 more
wiley +1 more source
Regional and Global Changes in Brain Structure 1‐Year Post Pediatric “Mild” Traumatic Brain Injury
Annals of Neurology, EarlyView.Objective Despite the high prevalence of pediatric “mild” traumatic brain injury (pmTBI), very little is known about the long‐term effects of injury on brain structure and how injuries manifest in the context of dynamic and regionally specific neurodevelopmental changes. Methods Prospective study design characterizing long‐term effects of pmTBI on both
Upasana Nathaniel +15 more
wiley +1 more source
eLife, 2019 Previously we showed that network-based modelling of brain connectivity interacts strongly with the shape and exact location of brain regions, such that cross-subject variations in the spatial configuration of functional brain regions are being ...
Janine Diane Bijsterbosch +4 more
doaj +1 more source
Brain Activations in Schizophrenia During a Graded Memory Task Studied With Functional Neuroimaging [PDF]
, 1998 Paul C. Fletcher +5 more
openalex +1 more source
Annals of Neurology, EarlyView.Objective A growing body of evidence indicates a strong genetic overlap between developmental and epileptic encephalopathies (DEEs) and movement disorders. De novo loss‐of‐function variants in NUS1 have been recently identified in DEE cases. Herein, we report a large cohort of cases with pathogenic NUS1 variants and describe their clinical presentation
Sarah M. Brooker +79 more
wiley +1 more source
Learning-related Neuronal Responses in Prefrontal Cortex Studied with Functional Neuroimaging [PDF]
, 1999 Paul C. Fletcher
openalex +1 more source
Functional neuroimaging of traumatic brain injury: advances and clinical utility
Neuropsychiatric Disease and Treatment, 2015 Functional deficits due to traumatic brain injury (TBI) can have significant and enduring consequences upon patients’ life quality and expectancy. Although functional neuroimaging is essential for understanding TBI pathophysiology, an insufficient amount
A. Irimia, J. V. Van Horn
semanticscholar +1 more source
HCN2‐Associated Neurodevelopmental Disorders: Data from Patients and Xenopus Cell Models
Annals of Neurology, EarlyView.Objective We aimed to characterize the phenotypic spectrum and functional consequences associated with variants in HCN2, encoding for the hyperpolarization‐activated cyclic nucleotide (HCN) gated channel 2. Methods GeneMatcher facilitated the recruitment of 21 individuals with HCN2 variants from 15 unrelated families, carrying HCN2 variants.
Clara Houdayer +52 more
wiley +1 more source
Annals of Neurology, EarlyView.Synthesis of Literature: Neurodegeneration in Moderate‐Severe TBI. Objective Although moderate‐to‐severe traumatic brain injury (msTBI) was once considered a static neural event following resolution of acute injuries, numerous studies now demonstrate progressive losses to volume and white matter integrity in the months and years postinjury, leading to ...
Bhanu Sharma +4 more
wiley +1 more source
Deep Brain Stimulation for VPS16‐Related Dystonia: A Multicenter Study
Annals of Neurology, EarlyView.Objective The objective was to evaluate the effects of deep brain stimulation (DBS) in an international cohort of patients with VPS16‐related dystonia. Methods This observational study collected preoperative and postoperative demographic, clinical, stimulation, genetic, neuroimaging, and neurophysiological data of medically refractory DYT‐VPS16 ...
Tatiana Svorenova +46 more
wiley +1 more source