Results 151 to 160 of about 4,562,205 (344)

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

open access: yesEpilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang   +3 more
wiley   +1 more source

Absence seizures: Update on signaling mechanisms and networks

open access: yesEpilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Effect of illness duration on cognitive function of OCD: a neuropsychological and functional neuroimaging study [PDF]

open access: gold, 2006
Tomohiro Nakao   +8 more
openalex   +1 more source

Dynamic electro‐clinical features in Guanidinoacetate N‐methyltransferase deficiency: A familial case series

open access: yesEpilepsia Open, EarlyView.
Abstract Guanidinoacetate N‐methyltransferase deficiency is an inborn error of creatine metabolism, responsible for the absent conversion of guanidinoacetic acid into creatine, resulting in cerebral creatine deficit. It could present a variety of symptoms such as neurodevelopmental delay, epilepsy, movement disorder (ataxia, dystonia, and chorea), and ...
Mariapaola Schifino   +5 more
wiley   +1 more source

Task-based functional neuroimaging in infants: a systematic review. [PDF]

open access: yesFront Neurosci, 2023
Agyeman K   +8 more
europepmc   +1 more source

The upside of epilepsy: Theories of an evolutionary paradox

open access: yesEpilepsia Open, EarlyView.
Abstract The persistence of common, heritable conditions, like epilepsy, that are associated with reduced reproductive fitness is an evolutionary paradox. Endogenous analgesic, anti‐depressant, and inflammatory mechanisms able to repair compromised functions can offer advantages in unexpected crises.
Alyssa Ailion   +3 more
wiley   +1 more source

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