Results 11 to 20 of about 5,006,415 (321)

Harmonizing results of ataxia rating scales: mFARS, SARA, and ICARS

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 2041-2046, December 2022., 2022
Abstract The ever‐increasing body of ataxia research provides opportunities for large‐scale meta‐analyses, systematic reviews, and data aggregation. Because multiple standardized scales are used to quantify ataxia severity, harmonization of these measures is necessary for quantitative data pooling. We applied the modified Friedreich Ataxia Rating Scale
Christian Rummey, Ian H. Harding, Martin B. Delatycki, Geneieve Tai, Thiago Rezende, Louise A. Corben   +5 more
wiley   +1 more source

Early‐onset Alzheimer's disease shows a distinct neuropsychological profile and more aggressive trajectories of cognitive decline than late‐onset

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1962-1973, December 2022., 2022
Abstract Objectives Early‐ and late‐onset Alzheimer's disease (EOAD and LOAD) share the same neuropathological traits but show distinct cognitive features. We aimed to explore baseline and longitudinal outcomes of global and domain‐specific cognitive function in a well characterized cohort of patients with a biomarker‐based diagnosis.
Adrià Tort‐Merino, Neus Falgàs, Isabel E. Allen, Mircea Balasa, Jaume Olives, José Contador, Magdalena Castellví, Jordi Juncà‐Parella, Núria Guillén, Sergi Borrego‐Écija, Bea Bosch, Guadalupe Fernández‐Villullas, Oscar Ramos‐Campoy, Anna Antonell, Lorena Rami, Raquel Sánchez‐Valle, Albert Lladó   +16 more
wiley   +1 more source

Limitations of functional neuroimaging for patient selection and surgical planning in glioma surgery.

Neurosurgical Focus, 2020
The optimal surgical management of gliomas requires a balance between surgical cytoreduction and preservation of neurological function. Preoperative functional neuroimaging, such as functional MRI (fMRI) and diffusion tensor imaging (DTI), has emerged as
T. Azad, H. Duffau
semanticscholar   +1 more source

The variability of functional MRI brain signal increases in Alzheimer's disease at cardiorespiratory frequencies

Scientific Reports, 2020
Biomarkers sensitive to prodromal or early pathophysiological changes in Alzheimer’s disease (AD) symptoms could improve disease detection and enable timely interventions. Changes in brain hemodynamics may be associated with the main clinical AD symptoms.
Timo Tuovinen, Janne Kananen, Zalan Rajna, Johannes Lieslehto, Vesa Korhonen, Riikka Rytty, Heli Mattila, Niko Huotari, Lauri Raitamaa, Heta Helakari, Ahmed Abou Elseoud, Johanna Krüger, Pierre LeVan, Osmo Tervonen, Juergen Hennig, Anne M. Remes, Maiken Nedergaard, Vesa Kiviniemi   +17 more
doaj   +1 more source

Functional Neuroimaging in Psychiatry—Aiding in Diagnosis and Guiding Treatment. What the American Psychiatric Association Does Not Know

Frontiers in Psychiatry, 2020
While early efforts in psychiatry were focused on uncovering the neurobiological basis of psychiatric symptoms, they made little progress due to limited ability to observe the living brain. Today, we know a great deal about the workings of the brain; yet,
Theodore A. Henderson, Muriel J. van Lierop, M. McLean, J. Uszler, John F. Thornton, Yin-Hui Siow, D. Pavel, Joe Cardaci, Phil Cohen   +8 more
semanticscholar   +1 more source

Feasibility and behavioral effects of prolonged static and dynamic standing as compared to sitting in older adults with type 2 diabetes mellitus

BMC Geriatrics, 2020
Background Physical inactivity is prevalent in older adults with type 2 diabetes mellitus (T2DM) and may exacerbate their clinical symptoms. The aim of this study was to examine the feasibility of 4-h regular versus more dynamic standing sessions while ...
Uros Marusic, Martijn L. T. M. Müller, Neil B. Alexander, Nicolaas I. Bohnen   +3 more
doaj   +1 more source

Thresholding of Statistical Maps in Functional Neuroimaging Using the False Discovery Rate

NeuroImage, 2002
Finding objective and effective thresholds for voxelwise statistics derived from neuroimaging data has been a long-standing problem. With at least one test performed for every voxel in an image, some correction of the thresholds is needed to control the ...
C. Genovese, N. Lazar, Thomas E. Nichols
semanticscholar   +1 more source

Where is the semantic system? A critical review and meta-analysis of 120 functional neuroimaging studies.

Cerebral Cortex, 2009
Semantic memory refers to knowledge about people, objects, actions, relations, self, and culture acquired through experience. The neural systems that store and retrieve this information have been studied for many years, but a consensus regarding their ...
J. Binder, Rutvik H. Desai, William W. Graves, L. Conant   +3 more
semanticscholar   +1 more source

Relevance of the anterior cingulate cortex volume and personality in motivated physical activity behaviors

Communications Biology, 2023
Some recent theories about the origins and maintenance of regular physical activity focus on the rewards of the properties of practicing this activity.
Anna Miró-Padilla, Jesús Adrián-Ventura, Anastasia Cherednichenko, Irene Monzonís-Carda, Maria Reyes Beltran-Valls, Diego MolinerUrdiales, César Ávila   +6 more
doaj   +1 more source

N‐back working memory paradigm: A meta‐analysis of normative functional neuroimaging studies

Human Brain Mapping, 2005
One of the most popular experimental paradigms for functional neuroimaging studies of working memory has been the n‐back task, in which subjects are asked to monitor the identity or location of a series of verbal or nonverbal stimuli and to indicate when
A. Owen, Kathryn M. McMillan, A. Laird, E. Bullmore   +3 more
semanticscholar   +1 more source