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The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang +12 more
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Functional neurological disorders: mechanisms and treatment
Functional neurological disorders are common problems in neurologic practice. In the past decade there has been an increasing interest in this group of disorders both from a clinical as well as research point of view. In this review, we highlight some of the most salient and exciting publications from recent years focusing especially on new findings ...
Jeannette Gelauff +2 more
exaly +8 more sources
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Functional Neurological Disorders
Neuroscience and Behavioral Physiology, 2022Background: Functional neurological disorders (FNDs) are common but often misdiagnosed. Review Summary: The incidence of FNDs is between 4 and 12 per 100,000, comparable to multiple sclerosis and amyotrophic lateral sclerosis, and it is the second most common diagnosis in neurology ...
S Yu Surushkina, L S Chutko
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Functional Neurological Disorder
Seminars in NeurologyAbstract Despite a long-documented history in psychology and psychiatry, functional neurological disorder (FND), also known as functional neurologic symptom disorder (FNSD) or “conversion disorder,” remains poorly understood. The experience of transient, unexplained neurological symptoms is normative in the general population and is not ...
Barbara A, Dworetzky +1 more
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Functional Neurological Disorders
Neuroscience and Behavioral Physiology, 2021This paper reviews the literature on functional neurological disorders (Dissociative (conversion disorders - F44). The authors present a change in views on the etiology and the main mechanisms of the pathogenesis of this pathology during the period of its study.
L S, Chutko, S Yu, Surushkina
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Functional neurological disorder: a review
British Dental Journal, 2023Functional neurological disorder is a common condition which may present to dental professionals. The dental team need to be aware of its varying presentation and the impact this can have on dental management. An overview on functional neurological disorder will be provided, as well as information regarding three patient cases.
Karishma, Dusara +2 more
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Functional Neurologic Disorders
Continuum, 2015Functional neurologic disorders, also called psychogenic, nonorganic, conversion, and dissociative disorders, are among the most common problems in neurologic practice. This article presents a practical guide to clinical assessment and treatment, incorporating emerging research evidence.
Jon, Stone, Alan, Carson
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