Results 41 to 50 of about 68,745 (263)

Functional tic-like presentations differ strikingly from Provisional Tic Disorder [version 2; peer review: 2 approved]

F1000Research, 2023
Background: Recent years have seen a dramatic increase in new “tic” cases in teens and young adults. These individuals often present with fulminant onset of symptoms not commonly seen in Tourette syndrome (TS) and are often diagnosed with Functional ...
Kevin J. Black, Emily C. Bihun, Amanda L. Arbuckle, Bradley L. Schlaggar   +3 more
doaj   +1 more source

Data_Sheet_1_Toward a possible trauma subtype of functional neurological disorder: Impact on symptom severity and physical health.docx

, 2022
BackgroundAs a group, individuals with functional neurological disorder (FND) report an approximately 3-fold increase in adverse life experiences (ALEs) compared to healthy controls.
Andrew J. Guthrie (14119059), David L. Perez (10095622), Sara Paredes-Echeverri (14119056)   +2 more
core   +1 more source

Functional neurological symptom disorder: Preliminary findings of factors associated with walking ability post integrative pediatric rehabilitation

Journal of Pediatric Rehabilitation Medicine, 2022
PURPOSE: The current study’s aims were to (1) examine long-distance walking ability (6-minute walking test [6MWT]) and walking hemodynamic responses (i.e., heart rate) among youth with functional neurological symptom disorder (FNSD) before and after an ...
Sharon Barak, Tamar Silberg, Maya Gerner, Etzyona Eisenstein, Chen Arzoni Bardach, Tamar Yissar, Jana Landa   +6 more
doaj   +1 more source

Emotion processing in functional neurological disorder [PDF]

, 2018
Objective: Alexithymia and hypomentalization, two traits associated with childhood emotional abuse/neglect, have not previously been studied in people with mixed-symptom functional neurological disorder (FND).
Coy, G.
core  

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Functional Neurological Symptom Disorder in Adolescents: A Case Report

Scholars Journal of Medical Case Reports, 2022
Functional neurological symptom disorder (FNSD) or conversion disorder (CD) as defined in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) include one or more symptoms of altered voluntary motor or sensory function. The diagnosis of CD was changed to FNSD and the definition has been updated since the last version of the DSM.
Rachid Rihab, Kenny Soukaina, El Hilali Yosra, Adali Imane, Manoudi Fatiha   +4 more
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Somatic symptom and related disorders in the Arab world: a narrative review of clinical features and care implications

Frontiers in Psychiatry
BackgroundSomatic symptom and related disorders (SSRDs) are prevalent worldwide, but their expression, help-seeking patterns, and management are strongly shaped by cultural context.
Mario Eid, Venise Abi Kheir, Maya Bizri, Amine Larnaout, Samer El Hayek, Samer El Hayek   +5 more
doaj   +1 more source

“Motoring in idle”: The default mode and somatomotor networks are overactive in children and adolescents with functional neurological symptoms

NeuroImage: Clinical, 2018
Objective: Children and adolescents with functional neurological symptom disorder (FND) present with diverse neurological symptoms not explained by a disease process. Functional neurological symptoms have been conceptualized as somatoform dissociation, a
Kasia Kozlowska, Chris J. Spooner, Donna M. Palmer, Anthony Harris, Mayuresh S. Korgaonkar, Stephen Scher, Leanne M. Williams   +6 more
doaj   +1 more source